S
Su-Fang Chen
Publications - 9
Citations - 18
Su-Fang Chen is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 2 publications receiving 8 citations.
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Journal Article
TJ0711, a novel vasodilatory β-blocker, protects SHR rats against hypertension induced renal injury
Juan Yang,Yong Ning,Jun Qiu,Jin-Seng He,Wei Li,Zufu Ma,Jufang Shao,Yue-Qiang Li,Rui Zeng,Meng Zhang,Jia Cheng,Su-Fang Chen,Gang Xu,Cong-Yi Wang,Ying Yao +14 more
TL;DR: TJ0711 improves kidney perfusion during the course of hypertensive insult by enhancing eNOS expression through suppressing inflammatory cytokine secretion and promotes HO-1 expression to protect SHR rats against oxidative stress induced by hypertension in the kidneys.
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Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex
Li-Qiong Xie,Yan-Mei Yuan,Simiao Xu,Sijia Lu,Jinyang Gu,Yanping Wang,Yibing Wang,Xianjing Zhang,Su-Fang Chen,Jian Li,Junxi Lu,Songlin Sun,Ruixiang Hu,Hai-long Piao,Wen Wang,Cunchuan Wang,Jing Xin Wang,Na Li,Morris F. White,Liu Han,Weiping Jia,Jianan Miao,Junli Liu +22 more
TL;DR: Younossi et al. as discussed by the authors revealed that copper restoration caused by hepatic ceruloplasmin (Cp) ablation enhances lipid catabolism by promoting the assembly of copper-load SCO1-LKB1-AMPK complex.
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Peroxisome Proliferator Activated Receptor Gamma Coactivator-1 Alpha: A Double-Edged Sword in Prostate Cancer.
TL;DR: The procancer and anticancer effects of PGC-1 α in PCA are highlighted and a theoretical basis for targeting AMPK/PGC-1α to inhibit the development of PCA is provided.
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Suppression of RIP1 activity via S415 dephosphorylation ameliorates obesity‐related hepatic insulin resistance
Yanping Wang,Jie Xiong,Yanmei Yuan,Chao Peng,Ping Wu,Yibing Wang,Junxi Lu,Yue Yin,Junting Xu,Su-Fang Chen,Junli Liu +10 more
TL;DR: Receptor‐interacting serine/threonine‐protein kinase 1 is a well‐documented key regulator of TNFα‐mediated inflammation, apoptosis, and necroptosis, which contribute to the development of obesity‐related metabolic diseases such as nonalcoholic steatohepatitis.
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Betaine–homocysteine methyltransferase promotes adipocyte commitment and insulin resistance via p38 MAPK/Smad signaling
Chuchu Liu,Yanping Wang,Junting Xu,Xing-Jie Liang,Jie Xiong,Sijia Lu,Peihui Zhou,Junli Liu,Su-Fang Chen +8 more
TL;DR: In this article , the authors investigated whether Betaine-homocysteine methyltransferase (Bhmt) participated in the development of obesity or its associated diabetes, as well as the mechanism involved.