Subhajit Maity

TL;DR: Histopathology and several blood parameters indicated that oral administrations of nanoparticles were free from toxicity and suggested that polymeric formulations were quite effective for oral delivery of the flavonoid as a therapeutic agent in the treatment of dyslipidemia, hyperglycemia and haemoglobin iron-mediated oxidative stress in type 1 diabetic model.

TL;DR: A pronounced hypoglycaemic effect and efficient maintenance of glucose homeostasis was evident in diabetic rat after peroral delivery of these quercetin nanoparticles in comparison to free oral quercets, suggesting the fabrication of an efficient carrier of oral quERCetin for diabetes treatment.

TL;DR: MG-derived AGEs may have an important role as the precursors of protein aggregation, which, in turn, may be associated with physiological complications.

TL;DR: How apoptotic pathways differentially regulate copper induced immunosuppression is demonstrated and the role of other partially responsible apoptotic molecules like p27, p73, p62, poly (ADP-ribose) polymerase (PARP) that differentially changed due to copper treatment in spleen and thymus of Swiss albino mice are identified.

TL;DR: Two cost effective polymers, sodium alginate and a modified chitosan derivative (succinyl chitOSan) were used for encapsulating quercetin through ionic crosslinking and showed pH sensitive and self-sustained release of encapsulated quercets, protecting it from the harsh environment and enzymatic deactivation in the gastrointestinal tract.