Sui Huang

TL;DR: It is concluded that endogenous IFN-gamma regulates the humoral isotype Ab pattern, but does not modulate the commitment of T cells to a Th2 phenotype in vivo or the acute infiltration of eosinophils to the lung.

TL;DR: This work curated human expression data and developed a data-driven method for identifying putative determinants of cell fate built around the concept of expression reversal of gene pairs, such as those participating in toggle-switch circuits.

TL;DR: Mechanical forces stimulate cell proliferation and vascular remodeling in living skin as cell growth and vascular supply are critical to wound healing and tissue expansion, devices applying controlled mechanical loads to tissues may be a powerful therapy to treat tissue defects.

TL;DR: In this paper, a method and devices for transmitting micromechanical forces locally to induce surface convolutions into tissues on the millimeter to micron scale for promoting wound healing are presented.

TL;DR: It is shown that endothelial-derived EETs play a critical role in accelerating tissue growth in vivo, including liver regeneration, kidney compensatory growth, lung compensatory Growth, wound healing, corneal neovascularization, and retinal vascularization, which indicates a central role for E ETs in organ and tissue regeneration and their contribution to tissue homeostasis.