S
Suk P. Oh
Researcher at University of Florida
Publications - 18
Citations - 4054
Suk P. Oh is an academic researcher from University of Florida. The author has contributed to research in topics: Type XVIII collagen & Collagen Type XVIII. The author has an hindex of 16, co-authored 18 publications receiving 3905 citations. Previous affiliations of Suk P. Oh include Gachon University & Harvard University.
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Journal ArticleDOI
Gene Dosage–Dependent Embryonic Development and Proliferation Defects in Mice Lacking the Transcriptional Integrator p300
Tso-Pang Yao,Suk P. Oh,Miriam Fuchs,Nai Dong Zhou,Lian Ee Ch'ng,D. Newsome,Roderick T. Bronson,En Li,David M. Livingston,Richard Eckner,Richard Eckner +10 more
TL;DR: Mouse development is exquisitely sensitive to the overall gene dosage of p300 and cbp, providing genetic evidence that a coactivator endowed with histone acetyltransferase activity is essential for mammalian cell proliferation and development.
Journal ArticleDOI
De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells.
TL;DR: A null mutation of the only known mammalian DNA methyltransferase gene is generated in mouse embryonic stem cells and it is found that the development of the homozygous embryos is arrested prior to the 8-somite stage, suggesting the existence of a second DNA methyl transferase in mammalian cells.
Journal ArticleDOI
The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse.
Suk P. Oh,En Li +1 more
TL;DR: It is shown that the ActRIIB-/- mice die after birth with complicated cardiac defects including randomized heart position, malposition of the great arteries, and ventricular and atrial septal defects, recapitulating the clinical symptoms of the human asplenia syndrome.
Journal ArticleDOI
Lack of collagen xviii/endostatin results in eye abnormalities
Naomi Fukai,Lauri Eklund,Alexander G. Marneros,Suk P. Oh,Douglas R. Keene,Lawrence Tamarkin,Merja Niemelä,Mika Ilves,En Li,Taina Pihlajaniemi,Bjorn R. Olsen +10 more
TL;DR: The findings provide an explanation for high myopia, vitreoretinal degeneration and retinal detachment seen in patients with Knobloch syndrome caused by loss‐of‐function mutations in collagen XVIII.
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Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension.
Anderson J. Ferreira,Vinayak Shenoy,Yoriko Yamazato,Srinivas Sriramula,Joseph Francis,Lihui Yuan,Ronald K. Castellano,David A. Ostrov,Suk P. Oh,Michael J. Katovich,Mohan K. Raizada +10 more
TL;DR: Conceptual support is provided that activation of ACE2 by a small molecule can be a therapeutically relevant approach for treating and controlling PH.