S
Sukant Garg
Researcher at National Institute of Advanced Industrial Science and Technology
Publications - 22
Citations - 346
Sukant Garg is an academic researcher from National Institute of Advanced Industrial Science and Technology. The author has contributed to research in topics: Cancer cell & Cancer. The author has an hindex of 8, co-authored 22 publications receiving 182 citations. Previous affiliations of Sukant Garg include University of Tsukuba & Max Planck Society.
Papers
More filters
Journal ArticleDOI
Cucurbitacin B and cancer intervention: Chemistry, biology and mechanisms (Review).
TL;DR: It is justifiable to propose cucurbitacin B as a mainline chemotherapy before the onset and after the diagnosis of cancer, through various molecular signaling pathways, as detailed in the below sections with summarized tables.
Journal ArticleDOI
Marine Carotenoid Fucoxanthin Possesses Anti-Metastasis Activity: Molecular Evidence.
Sukant Garg,Sajal Afzal,Ahmed Elwakeel,Damini Sharma,Navaneethan Radhakrishnan,Jaspreet Kaur Dhanjal,Durai Sundar,Sunil C. Kaul,Renu Wadhwa +8 more
TL;DR: Investigation of fucoxanthin activities in human cancer cell culture-based viability, migration, and molecular assays found that it possesses strong anticancer and anti-metastatic activities that work irrespective of the p53 status of cancer cells.
Journal ArticleDOI
CARF enrichment promotes epithelial–mesenchymal transition via Wnt/β-catenin signaling: its clinical relevance and potential as a therapeutic target
Rajkumar Singh Kalra,Anupama Chaudhary,A-Rum Yoon,Priyanshu Bhargava,Amr Omar,Sukant Garg,Chae-Ok Yun,Sunil C. Kaul,Renu Wadhwa +8 more
TL;DR: Clinical and therapeutic relevance of CARF in EMT and cancer invasiveness/metastasis are reported, and it is proposed as a potent therapeutic target of aggressive cancers.
Journal ArticleDOI
Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential.
Sukant Garg,Sukant Garg,He Huifu,He Huifu,Anjani Kumari,Durai Sundar,Sunil C. Kaul,Renu Wadhwa,Renu Wadhwa +8 more
TL;DR: It is proposed that CucWi-N is a potential natural anticancer drug that warrants further mechanistic and clinical studies and possesses high capability to target mortalin-p53 interaction and hnRNP-K proteins.
Journal ArticleDOI
Functional Characterisation of Anticancer Activity in the Aqueous Extract of Helicteres angustifolia L. Roots
Kejuan Li,Kejuan Li,Kejuan Li,Yue Yu,Yue Yu,Shuang Sun,Ye Liu,Sukant Garg,Sukant Garg,Sunil C. Kaul,Zhongfang Lei,Ran Gao,Renu Wadhwa,Renu Wadhwa,Zhenya Zhang +14 more
TL;DR: In vivo xenograft tumor assays in nude mice revealed dose-dependent suppression of tumor growth and lung metastasis with no toxicity to the animals suggesting that AQHAR could be a potent and safe natural drug for cancer treatment.