Sultan Alasmari

TL;DR: This study performs an exhaustive phylogenetic analysis in a highly purified and functionally defined cell type comprising neutrophilic granulocytes from five vertebrate species spanning 430 million years of evolution to suggest that intron-retaining genes are transcriptionally co-regulated from bidirectional promoters.

TL;DR: It is demonstrated that the macrophage intracellular niche favours infection establishment by protecting conidia from a myeloperoxidase-dependent neutrophil fungicidal activity, and a new in vivo model of talaromycosis with several advantages over previous models is provided.

TL;DR: The potential of zebrafish as an inflammatory lymphangiogenesis model that can be used to investigate the role and mechanism of lymphang iogenesis in inflammatory diseases such as IBD is highlighted.

TL;DR: In this article, the authors demonstrate that neutrophil swarming is a conserved process in zebrafish immunity, sharing essential features with mammalian systems, and they use a photoconversion approach to track neutrophils within developing swarms, identifying the fate of swarm-initiating pioneer neutrophILS involves extracellular chromatin release and that the key NET components gasdermin, neutrophIL elastase, and myeloperoxidase are required for the swarming process.

TL;DR: A model called the detecting model for liver damage (DMLD) that predicts the risk of liver damage in COVID-19 ICU patients and applies machine learning algorithms in order to assess therisk of liver failure based on patient data is proposed.