S
Suman Khan
Researcher at Weizmann Institute of Science
Publications - 4
Citations - 785
Suman Khan is an academic researcher from Weizmann Institute of Science. The author has contributed to research in topics: Endosome & Lipid bilayer fusion. The author has an hindex of 1, co-authored 1 publications receiving 22 citations.
Papers
More filters
Journal ArticleDOI
SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses
Wanwisa Dejnirattisai,Jiandong Huo,D. Zhou,Jiří Zahradník,P Supasa,Changxiao Liu,Helen M. E. Duyvesteyn,Helen M. Ginn,Alexander J. Mentzer,Aekkachai Tuekprakhon,Rungtiwa Nutalai,Beibei Wang,Aiste Dijokaite,Suman Khan,Ori Avinoam,M.W. Bahar,Donal T. Skelly,S Adele,Síle A. Johnson,Thomas G Ritter,Chris Jb Mason,Christina Dold,Daniel Pan,Sara Assadi,A. Bellass,Nikki Omo-Dare,David Koeckerling,Amy Flaxman,D Jenkin,Parvinder K. Aley,Merryn Voysey,Sue Ann Costa Clemens,Felipe Gomes Naveca,Valdinete Alves do Nascimento,Fernanda Nascimento,Cristiano Fernandes da Costa,Paola Cristina Resende,Alex Pauvolid-Corrêa,Marilda M. Siqueira,Vicky L. Baillie,Natali Serafin,Gaurav Kwatra,Kelly Da Silva,Shabir A. Madhi,Marta C. Nunes,Tariq Mehmood Malik,Peter J. M. Openshaw,J Kenneth Baillie,Malcolm G Semple,Alain Townsend,Kuan-Ying A. Huang,Tiong Kit Tan,Miles W. Carroll,Paul Klenerman,Eleanor Barnes,Susanna Dunachie,Bede Constantinides,Hermione J. Webster,Derrick W. Crook,Andrew J. Pollard,Teresa Lambe,Neil G. Paterson,Mark Williams,Elizabeth E. Fry,Juthathip Mongkolsapaya,Jingshan Ren,Gideon Schreiber,David Stuart,Gavin R. Screaton +68 more
TL;DR: In this article , a new SARS-CoV-2 viral isolate Omicron-B.1.529 was announced, containing far more mutations in Spike (S) than previously reported variants, leading to a large number of mutations in the ACE2 binding site and rebalances receptor affinity to that of earlier pandemic viruses.
Journal ArticleDOI
Golgi organization is regulated by proteasomal degradation.
Avital Eisenberg-Lerner,Ron Benyair,Noa Hizkiahou,Neta Nudel,Roey Maor,Matthias P. Kramer,Merav D. Shmueli,Inbal Zigdon,Marina Cherniavsky Lev,Adi Ulman,Jitka Yehudith Sagiv,Molly Dayan,Bareket Dassa,Mercedes Rosenwald,Idit Shachar,Jie Li,Yanzhuang Wang,Nili Dezorella,Suman Khan,Ziv Porat,Eyal Shimoni,Ori Avinoam,Yifat Merbl +22 more
TL;DR: Stress-induced degradation of GM130 by Golgi-localized 26S proteasomes, leading to Golgi dispersal is identified, providing a functional link between proteostasis control and Golgi architecture, which may be critical in various secretion-related pathologies.
Journal ArticleDOI
Extracellular vesicle fusion visualized by cryo-electron microscopy
Mattia I. Morandi,P. B. Busko,Efrat Ozer-Partuk,Suman Khan,Giulia Zarfati,Yael Elbaz-Alon,Paula Abou Karam,Tina Napso Shogan,Lana Ginini,Ziv Gil,Neta Regev-Rudzki,Ori Avinoam +11 more
TL;DR: In this article , the authors developed and benchmarked an in vitro biophysical assay to investigate extracellular vesicles (EVs) membrane fusion and showed that EVs and retroviruses fuse with liposomes mimicking the membrane composition of the late endosome in a pH-and protein-dependent manner.
Posted ContentDOI
Extracellular vesicle fusion visualized by cryo-EM
Mattia I. Morandi,P. B. Busko,Efrat Ozer-Partuk,Suman Khan,Giulia Zarfati,Yael Elbaz-Alon,Paula Abou Karam,Tina Napso Shogan,Lana Ginini,Ziv Gil,Neta Regev-Rudzki,Ori Avinoam +11 more
TL;DR: It is found that, unlike most retroviruses, EVs remain fusogenic after acidification and re-neutralization and provide novel insights into the EV cargo delivery mechanism and an experimental approach to identify the EV fusion machinery.