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Suraporn Matragoon

Researcher at University of Georgia

Publications -  54
Citations -  2214

Suraporn Matragoon is an academic researcher from University of Georgia. The author has contributed to research in topics: Nerve growth factor & Peroxynitrite. The author has an hindex of 27, co-authored 54 publications receiving 2061 citations. Previous affiliations of Suraporn Matragoon include Veterans Health Administration & Georgia Regents University.

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Neuroprotective Effect of(−)Δ9-Tetrahydrocannabinol and Cannabidiol in N-Methyl-d-Aspartate-Induced Retinal Neurotoxicity : Involvement of Peroxynitrite

TL;DR: The potential use of CBD as a novel topical therapy for the treatment of glaucoma is suggested and the hypothesis that glutamate causes apoptosis of retinal neurons via the excessive formation of peroxynitrite is tested.
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Retinal Microglial Activation and Inflammation Induced by Amadori-Glycated Albumin in a Rat Model of Diabetes

TL;DR: It is shown that formation of reactive oxygen species and subsequent activation of ERK and P38, but not Jun NH2-terminal kinase, are molecular events underpinning retinal microglial TNF-α release during AGA treatment, providing new insights in understanding the pathogenesis of early DR.
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Role of NADPH Oxidase and Stat3 in Statin-Mediated Protection against Diabetic Retinopathy

TL;DR: The results suggest that simvastatin protects against the early signs of diabetic retinopathy by preventing NADPH oxidase-mediated activation of STAT3.
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Peroxynitrite Mediates Retinal Neurodegeneration by Inhibiting Nerve Growth Factor Survival Signaling in Experimental and Human Diabetes

TL;DR: The data suggest that diabetes-induced peroxynitrite impairs NGF neuronal survival by nitrating TrkA receptor and enhancing p75NTR expression, and suggests that FeTPPS prevented tyrosine nitration, restored NGF survival signal, and prevented neuronal death in vitro and in vivo.
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Early Onset Photoreceptor Abnormalities Induced by Targeted Disruption of the Interphotoreceptor Retinoid-Binding Protein Gene

TL;DR: Observations indicate that normal photoreceptor development and function are highly dependent on the early expression of IRBP, and that in the absence ofIRBP there is a slowly progressive degeneration of retinal photoreceptors.