S
Susan C. Shelmerdine
Researcher at UCL Institute of Child Health
Publications - 111
Citations - 1244
Susan C. Shelmerdine is an academic researcher from UCL Institute of Child Health. The author has contributed to research in topics: Medicine & Computer science. The author has an hindex of 13, co-authored 91 publications receiving 740 citations. Previous affiliations of Susan C. Shelmerdine include National Institute for Health Research & Great Ormond Street Hospital for Children NHS Foundation Trust.
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Journal ArticleDOI
Effects of Ivacaftor in Patients With Cystic Fibrosis Who Carry the G551D Mutation and Have Severe Lung Disease
Peter J. Barry,Barry J. Plant,Barry J. Plant,Barry J. Plant,Arjun Nair,Stephen Bicknell,Nicholas J. Simmonds,N.J. Bell,Nadia Shafi,T. Daniels,Susan C. Shelmerdine,Imogen C. Felton,Cedric Gunaratnam,Andrew Jones,Alex Horsley +14 more
TL;DR: Ivacaftor was clinically effective in patients with CF who carry the G551D mutation and have severe pulmonary disease and the reductions in treatment requirements were clinically and statistically significant and have not been described in less severe populations.
Journal ArticleDOI
Thoracic imaging of coronavirus disease 2019 (COVID-19) in children: a series of 91 cases.
Pablo Caro-Domínguez,Susan C. Shelmerdine,Susan C. Shelmerdine,Seema Toso,Aurelio Secinaro,Paolo Tomà,Maria Beatrice Damasio,María Navallas,Lucia Riaza-Martin,David Gomez-Pastrana,Maryam Ghadimi Mahani,Sarah M. Desoky,Carlos F. Ugas Charcape,Judith Almanza-Aranda,Maria Elena Ucar,Jovan Lovrenski,Süreyya Burcu Görkem,Efthymia Alexopoulou,Pierluigi Ciet,Joost van Schuppen,Hubert Ducou Le Pointe,Hyun Woo Goo,Christian J. Kellenberger,Maria Raissaki,Catherine M. Owens,Catherine M. Owens,Franz Wolfgang Hirsch,Rick R. van Rijn +27 more
TL;DR: It seems unnecessary to perform chest imaging in children to diagnose COVID-19, and CT should be reserved for when there is clinical concern to assess for possible complications, especially in children with coexisting medical conditions.
Journal ArticleDOI
Coronavirus disease 2019 (COVID-19) in children: a systematic review of imaging findings.
TL;DR: CT chest findings in children with COVID-19 are frequently normal or mild, and lower lobes are predominantly affected by patchy ground-glass opacification.
Journal ArticleDOI
Postmortem microfocus computed tomography for early gestation fetuses: a validation study against conventional autopsy
John C Hutchinson,Xin Kang,Susan C. Shelmerdine,Valérie Segers,CM Lombardi,Mieke Cannie,Neil J. Sebire,Jacques Jani,Owen J. Arthurs,Owen J. Arthurs +9 more
TL;DR: Postmortem whole body fetal microfocus computed tomography gave noninvasive autopsy in minutes, at a mean resolution of 27&mgr;m, with high diagnostic accuracy in fetuses at <22 weeks gestation, and may be preferable to magnetic resonance imaging in early gestation fetuses.
Journal ArticleDOI
Stresses and strains on the human fetal skeleton during development
Stefaan W. Verbruggen,Bernhard Kainz,Susan C. Shelmerdine,Joseph V. Hajnal,Mary A. Rutherford,Owen J. Arthurs,Andrew N. Phillips,Niamh C. Nowlan +7 more
TL;DR: This research represents the first quantification of kick force and mechanical stress and strain due to fetal movements in the human skeleton in utero, thus advancing the understanding of the biomechanical environment of the uterus.