A
Alex Horsley
Researcher at University of Manchester
Publications - Â 148
Citations - Â 4865
Alex Horsley is an academic researcher from University of Manchester. The author has contributed to research in topics: Cystic fibrosis & Medicine. The author has an hindex of 27, co-authored 119 publications receiving 3170 citations. Previous affiliations of Alex Horsley include Manchester Academic Health Science Centre & Western General Hospital.
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Journal ArticleDOI
Consensus statement for inert gas washout measurement using multiple- and single- breath tests
Paul Robinson,Philipp Latzin,Sylvia Verbanck,Graham L. Hall,Alex Horsley,Monika Gappa,Cindy Thamrin,Hubertus G.M. Arets,Paul Aurora,Susanne I. Fuchs,Gregory G. King,Sooky Lum,Kenneth G. MacLeod,Manuel Paiva,J. Jane Pillow,Sarath Ranganathan,Felix Ratjen,Florian Singer,Samatha Sonnappa,Janet Stocks,Padmaja Subbarao,Bruce Thompson,P. Gustafsson +22 more
TL;DR: Recommendations are provided about these aspects, applicable to both the paediatric and adult testing environment, whilst outlining the important principles that are essential for the reader to understand.
Journal ArticleDOI
COVID-19 vaccine coverage in health-care workers in England and effectiveness of BNT162b2 mRNA vaccine against infection (SIREN): a prospective, multicentre, cohort study.
Victoria Hall,Victoria Hall,Sarah Foulkes,Ayoub Saei,Nick Andrews,Nick Andrews,Blanche Oguti,Blanche Oguti,Andre Charlett,Andre Charlett,Andre Charlett,Edgar Wellington,Julia Stowe,Natalie Gillson,Ana Atti,Jasmin Islam,Ioannis Karagiannis,Katie Munro,Jameel Khawam,Meera Chand,Colin S Brown,Mary Ramsay,Mary Ramsay,Jamie Lopez-Bernal,Susan Hopkins,Susan Hopkins,N Andrews,A Atti,H Aziz,Tim Brooks,CS Brown,D Camero,C Carr,MA Chand,A Charlett,Hayley Crawford,Michael J. Cole,J Conneely,Silvia D'Arcangelo,Joanna Ellis,S Evans,S Foulkes,N Gillson,Robin Gopal,L Hall,V J Hall,P Harrington,Susan R. Hopkins,Jacqueline Hewson,Katja Hoschler,D Ironmonger,J Islam,Meaghan Kall,I Karagiannis,O Kay,J Khawam,E King,Peter Kirwan,R Kyffin,Angie Lackenby,M Lattimore,Ezra Linley,J Lopez-Bernal,L Mabey,Reuben McGregor,Shahjahan Miah,Ejm Monk,K Munro,Z Naheed,A Nissr,A M O'Connell,B Oguti,Henrietta U. Okafor,S Organ,J Osbourne,Ashley Otter,Minal Patel,Steven Platt,D Pople,K Potts,M Ramsay,Julie V. Robotham,Sakib Rokadiya,Cathy Rowe,A Saei,G Sebbage,Amanda Semper,Madhumita Shrotri,Ruth Simmons,Alex Soriano,P Staves,S Taylor,Arthur Taylor,A Tengbe,S Tonge,Amoolya Vusirikala,Sarah Wallace,E Wellington,Maria Zambon,D Corrigan,M Sartaj,L Cromey,Sharon Campbell,K Braithwaite,L Price,L Haahr,S Stewart,ED Lacey,Linda Partridge,Gretchen A Stevens,Y Ellis,H Hodgson,C Norman,B Larru,S Mcwilliam,A Roynon,J Northfield,Stephen Winchester,P Cieciwa,Aditi Pai,P Bakker,C Loughrey,A Watt,F Adair,Adrian Hawkins,Alastair Grant,R Temple-Purcell,J Howard,N Slawson,C Subudhi,Shân Davies,A Bexley,R Penn,N Wong,G Boyd,A Rajgopal,A Arenas-Pinto,R Matthews,A Whileman,R Laugharne,J Ledger,Trevor J. Barnes,Chris Jones,N Osuji,N Chitalia,T Bailey,S Akhtar,G Harrison,S Horne,Naomi F. Walker,Ken Agwuh,V Maxwell,J Graves,Stephen R. Williams,A O'Kelly,P Ridley,A Cowley,H Johnstone,P Swift,Jane Democratis,Manjula Meda,S Brake,J Gunn,A Selassi,S Hams,V Irvine,Badrinathan Chandrasekaran,C Forsyth,J Radmore,C Thomas,Kevin K. Brown,Stuart K. Roberts,P Burns,K Gajee,T Lewis,T M Byrne,F Sanderson,Stephen R Knight,Emily MacNaughton,Bjl Burton,Helen V. Smith,R Chaudhuri,J Aeron-Thomas,K Hollinshead,R.J. Shorten,A Swan,C Favager,J Murira,S Baillon,S Hamer,Aarti Shah,J Russell,D Brennan,A Dave,Ajay Chawla,F Westwell,D Adeboyeku,Padmasayee Papineni,C Pegg,Martin S. Williams,Shazaad Ahmad,Alex Horsley,Christian Gabriel,K Pagget,G Maloney,J Ashcroft,I Del Rosario,R Crosby-Nwaobi,D Flanagan,D Dhasmana,Stephen J. Fowler,E Cameron,L Prentice,C Sinclair,V Bateman,K McLelland-Brooks,A Ho,Michael P. Murphy,A Cochrane,A Gibson,K. Black,K Tempeton,Stacey Donaldson,L Coke,N Elumogo,J Elliott,Debra Padgett,A Cross,Mariyam Mirfenderesky,S Joyce,I Sinanovic,M Howard,P Cowling,M Brazil,E Hanna,A Abdelrazik,S Brand,EA Sheridan,B Wadams,A Lloyd,J Mouland,J Giles,G Pottinger,H Coles,Mark Joseph,M Lee,S Orr,H Chenoweth,D Browne,Cressida Auckland,R Lear,Tabitha Mahungu,Alison Rodger,Simon Warren,D Brooking,S Pai,R Druyeh,Edward M. Smith,S. Stone,Sarah Meisner,D Delgado,E Underhill,L Keen,M Aga,P Domingos,S Gormley,Caroline Kerrison,S Birch,T DeSilva,L Allsop,S Ambalkar,M Beekes,S Jose,J Tomlinson,Sharen Painter,Claire Price,Justin Pepperell,Keith D. James,T Trinick,L Moore,Jeremy N. Day,A Boulos,I Knox,E Defever,D McCracken,K Gray,A Houston,Tim Planche,R Pritchard Jones,Diane Wycherley,Sara Bennett,J Marrs,K Nimako,Benjamin J. Stewart,SC Bain,N Kalakonda,S Khanduri,A Ashby,Matthew T. G. Holden,N Mahabir,J Harwood,Brendan A I Payne,K Court,Nicholas J. White,R Longfellow,L E Hughes,M E Green,M Halkes,P Mercer,A Roebuck,Eleri Wilson-Davies,L Gallego,Rajeka Lazarus,N Aldridge,Louise Berry,Frances L. Game,Timothy M Reynolds,Christopher W Holmes,Martin Wiselka,A Higham,M Booth,C Duff,J Alderton,D Hilton,J Powell,Alan Jackson,AJ Plant,Nada Ahmed,T Chin,M Z Qazzafi,A M Moody,Robert Tilley,T Donaghy,M O'Kane,K Shipman,R Sierra,Chetan Parmar,Gordon B. Mills,Daniel Harvey,Ywj Huang,J Birch,Louise Robinson,S Board,A Broadley,C Laven,N Todd,David W Eyre,Katie Jeffery,Susanna Dunachie,Christopher J A Duncan,Paul Klenerman,Lance Turtle,Helen Baxendale,Jonathan L. Heeney +353 more
TL;DR: The SIREN study as discussed by the authors showed that the BNT162b2 vaccine can prevent both symptomatic and asymptomatic infection in working-age adults in the UK.
Journal ArticleDOI
Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.
Rachael A. Evans,Hamish McAuley,Ewen M Harrison,Aarti Shikotra,Amisha Singapuri,Marco Sereno,Omer Elneima,Annemarie B Docherty,Nazir I Lone,Nazir I Lone,Olivia C. Leavy,Luke Daines,J Kenneth Baillie,J Kenneth Baillie,Jeremy S. Brown,Trudie Chalder,Anthony De Soyza,Nawar Diar Bakerly,Nawar Diar Bakerly,Nicholas Easom,John R. Geddes,John R. Geddes,Neil J. Greening,Nicholas Hart,Liam G Heaney,Liam G Heaney,Simon Heller,Luke Howard,John R. Hurst,Joseph Jacob,R. Gisli Jenkins,Caroline J. Jolley,Steven Kerr,Onn Min Kon,Onn Min Kon,Keir Lewis,Janet M. Lord,Gerry P McCann,Stefan Neubauer,Peter J. M. Openshaw,Dhruv Parekh,Dhruv Parekh,Paul E Pfeffer,Paul E Pfeffer,Najib M. Rahman,Betty Raman,Matthew Richardson,Matthew J. Rowland,Malcolm G Semple,Malcolm G Semple,Ajay M. Shah,Sally J Singh,Aziz Sheikh,David B. Thomas,Mark Toshner,James D. Chalmers,Ling-Pei Ho,Alex Horsley,Michael Marks,Michael Marks,Krisnah Poinasamy,Louise V. Wain,Christopher E. Brightling,Kathryn M. Abel,Huzaifa Adamali,Davies Adeloye,O Adeyemi,F Adeyemi,S Ahmad,R Ahmed,M Ainsworth,A Alamoudi,M Aljaroof,Louise Allan,R Allen,A Alli,B Al-Sheklly,D Altmann,Denise Anderson,M Andrews,A Angyal,Charalambos Antoniades,Gill Arbane,Cherie Armour,N Armstrong,Lynne Armstrong,H Arnold,David T Arnold,Milton Ashworth,A Ashworth,H Assefa-Kebede,P Atkin,H Atkins,A Atkins,R Aul,C Avram,R Baggott,D Baguley,J K Baillie,S Bain,M Bakali,M Bakau,Emma Baldry,David R Baldwin,Clive Ballard,J Bambrough,Ruth E Barker,Shaney L Barratt,F Barrett,N Basu,Rachel L. Batterham,H Baxendale,Hannah Bayes,M Bayley,Michael Beadsworth,P Beirne,R Bell,Derek Bell,Colin Berry,S Betts,K Bhui,L Bishop,J Blaikely,C Bloomfield,A Bloss,A Bolger,C E Bolton,J Bonnington,A Botkai,M Bourne,C Bourne,E Bradley,K Bramham,L Brear,Gerome Breen,J Breeze,A Briggs,E Bright,C E Brightling,Simon E. Brill,K Brindle,L Broad,M Broome,J S Brown,Matthew A. Brown,Jamie Brown,Richard G. Brown,V Brown,Ashley C. Brown,Traolach S. Brugha,Nigel J. Brunskill,M Buch,A Bularga,Edward T. Bullmore,David J. Burn,G Burns,Jonathan P. Busby,A.J. Buttress,S Byrne,P Cairns,P C Calder,E Calvelo,B Card,L Carr,Gail Carson,Patrice Carter,J Cavanagh,T Chalder,J D Chalmers,Rachel C. Chambers,Keith M. Channon,Kath Chapman,A Charalambou,N Chaudhuri,A Checkley,J Chen,L Chetham,E R Chilvers,H Chinoy,K Chong-James,N Choudhury,G Choudhury,P Chowdhury,P Chowienczyk,C Christie,David W. Clark,C. Clark,Judith Clarke,P Clift,Sara Clohisey,Z Coburn,John B. Cole,C Coleman,D W Connell,B Connolly,Lynda Connor,Angela Cook,Brendan G Cooper,C Coupland,T Craig,P Crisp,D. Cristiano,M G Crooks,A Cross,I Cruz,Paul Cullinan,L Daines,M Dalton,Paul Dark,J. Dasgin,Asaf David,C David,Melanie J. Davies,Gail Davies,Kevin A. Davies,F. Davies,G A Davies,Enya Daynes,T I de Silva,A De Soyza,Bill Deakin,A Deans,S Defres,Anne Dell,K Dempsey,Joe Dennis,A Dewar,R Dharmagunawardena,N Diar Bakerly,A Dipper,S Diver,S N Diwanji,M Dixon,R Djukanovic,H Dobson,C Dobson,S L Dobson,A B Docherty,Andrew Donaldson,T Dong,N. Dormand,A Dougherty,R Dowling,S Drain,P Dulawan,S Dunn,N Easom,C Echevarria,Sebastian Edwards,Charlotte L. Edwardson,B Elliott,Amanda F. Elliott,Y Ellis,A Elmer,O Elneima,R A Evans,Julie Evans,H Evans,David M. Evans,R I Evans,R Evans,Todd Evans,L Fabbri,S Fairbairn,A Fairman,K Fallon,D Faluyi,C Favager,Timothy Felton,Jonathan Finch,S Finney,Helen L. Fisher,Shelley Fletcher,R Flockton,D Foote,A Ford,D Forton,Richard W. Francis,S Francis,C Francis,A Frankel,E Fraser,R Free,N French,J Fuld,James J Furniss,L Garner,Nikki Gautam,J R Geddes,P M George,Jeremy George,M Gibbons,L Gilmour,Fergus V. Gleeson,J Glossop,S Glover,N Goodman,B Gooptu,T. Gorsuch,E Gourlay,P Greenhaff,William Greenhalf,A Greenhalgh,N J Greening,John P Greenwood,S Greenwood,R Gregory,Douglas Grieve,M. Gummadi,Atul Gupta,S Gurram,Ellen Guthrie,K Hadley,A Haggar,K Hainey,P Haldar,I Hall,Lynsey S. Hall,M Halling-Brown,R Hamil,N A Hanley,Hayley Hardwick,Elaine Hardy,B Hargadon,Kyle Harrington,V Harris,E M Harrison,Phil Harrison,N Hart,Alison G. Harvey,Miriam Harvey,M Harvie,M Havinden-Williams,J Hawkes,N Hawkings,J Haworth,A Hayday,L G Heaney,J L Heeney,Melissa Heightman,S Heller,Morag Henderson,L Hesselden,Toby Hillman,Aroon D. Hingorani,T Hiwot,L P Ho,A Hoare,M Hoare,P Hogarth,A Holbourn,L Holdsworth,D Holgate,K Holmes,B Holroyd-Hind,A Horsley,A Hosseini,Matthew Hotopf,L Houchen,Louise M. Howard,A Howell,E Hufton,Alan Hughes,Joseph Hughes,R Hughes,A Humphries,N Huneke,J R Hurst,R Hurst,Mujtaba Husain,T Hussell,W Ibrahim,A Ient,L Ingram,Khalida Ismail,Thomas A Jackson,J Jacob,W Y James,Sam M. Janes,H Jarvis,B Jayaraman,R G Jenkins,Peter Jezzard,K Jiwa,Sonia Johnson,Craig Johnson,D Johnston,C Jolley,C J Jolley,Ifan Jones,S Jones,D Jones,H Jones,Graeme Jones,Margaret Jones,S. Jose,Thomas Kabir,G Kaltsakas,Vicky Kamwa,P Kar,Z Kausar,Siobhan Kelly,S Kerr,A L Key,F Khan,Kamlesh Khunti,C King,B King,P Kitterick,Paul Klenerman,L Knibbs,Stephen R Knight,A Knighton,O M Kon,S Kon,S S Kon,Ania Korszun,Christos P Kotanidis,I Koychev,P Kurupati,J Kwan,C Laing,H Lamlum,Geraldine Landers,Claudia Langenberg,Daniel Lasserson,Alison M. Lawrie,A Lea,O C Leavy,Donghyung Lee,E Lee,K Leitch,R Lenagh,K Lewis,V Lewis,K E Lewis,J Lewis,N Lewis-Burke,Teresa Light,L Lightstone,L Lim,S Linford,A Lingford-Hughes,Marc Lipman,K. Liyanage,A Lloyd,S Logan,David A. Lomas,N I Lone,R. Loosley,J M Lord,H Lota,A Lucey,G MacGowan,I Macharia,Clare E. Mackay,Linda MacLiver,Shyam Madathil,G Madzamba,N Magee,N Mairs,N Majeed,E Major,M Malim,G Mallison,W Man,Swapna Mandal,K Mangion,P Mansoori,S Marciniak,M Mariveles,M Marks,Ben G. Marshall,A Martineau,Nick A Maskell,D Matila,L Matthews,J Mayet,S McAdoo,H McAllister-Williams,P McArdle,A McArdle,D McAulay,H McAuley,Daniel F. McAuley,K McCafferty,G P McCann,H McCauley,P McCourt,L Mcgarvey,J McGinness,A McGovern,H. McGuinness,Iain B. McInnes,K McIvor,E McIvor,Alex D. McMahon,M J McMahon,L. McMorrow,T Mcnally,M McNarry,A McQueen,Helen McShane,S Megson,J Meiring,Donna J. Menzies,A Michael,L Milligan,N Mills,James E. Mitchell,A Mohamed,Philip L. Molyneaux,William Monteiro,A Morley,L Morrison,R Morriss,Ardythe L. Morrow,A Moss,A J Moss,Paul Moss,Elizabeta B. Mukaetova-Ladinska,U Munawar,Elodie Murali,J Murira,H Nassa,P Neill,S Neubauer,David E. Newby,H Newell,A Newton Cox,Timothy R Nicholson,D Nicoll,Claire M. Nolan,M J Noonan,P. Novotny,J Nunag,J Nyaboko,L. O'Brien,N Odell,G Ogg,O Olaosebikan,C Oliver,Z. Omar,Peter J. M. Openshaw,P Rivera-Ortega,R Osbourne,Marlies Ostermann,C Overton,J Oxton,E Pacpaco,S Paddick,Padmasayee Papineni,K Paradowski,M Pareek,D Parekh,H Parfrey,Carmine M. Pariante,Stephen C. J. Parker,Margot W. Parkes,J Parmar,R Parvin,S Patale,Brij Patel,Smitaa Patel,Meenal Patel,B Pathmanathan,Michael Pavlides,J E Pearl,Daniel Peckham,J. Pendlebury,Y Peng,Catherine Pennington,I Peralta,E. Perkins,T Peto,Nayia Petousi,John R. Petrie,P Pfeffer,J Phipps,Jonathan Pimm,K Piper Hanley,R Pius,S Plein,T Plekhanova,K Poinasamy,Oliver Polgar,L Poll,J C Porter,S Portukhay,N Powell,L Price,David Price,Anthony N. Price,C. Price,A Prickett,S. Quaid,J Quigley,Jennifer K Quint,H Qureshi,N Rahman,M Rahman,M Ralser,B Raman,A Ramos,J Rangeley,Tim Rees,K Regan,Alexander Richards,M Richardson,E Robertson,J Rodgers,G Ross,J Rossdale,Anthony J. Rostron,A Routen,A Rowland,M J Rowland,J Rowland,S L Rowland-Jones,K Roy,Igor Rudan,R Russell,E. Russell,R Sabit,E K Sage,Nilesh J. Samani,R Samuel,E Sapey,D Saralaya,A Saratzis,Jack A. Sargeant,T Sass,Naveed Sattar,Kathryn J Saunders,R Saunders,W Saxon,Avan Aihie Sayer,W Schwaeble,Janet T Scott,K Scott,N Selby,Malcolm G Semple,M Sereno,Khalid Shah,A. J. Shah,P Shah,Manu Sharma,Michael Sharpe,C Sharpe,V Shaw,A Sheikh,K Shevket,A Shikotra,Jennifer M. Short,Salman Siddiqui,Louise Sigfrid,G Simons,J Simpson,A Singapuri,S J Singh,C Singh,S Singh,J Skeemer,I Smith,Jennifer A. Smith,Lee B. Smith,Andrew Smith,Marcia Soares,D Southern,M Spears,L G Spencer,F Speranza,Louise Stadon,S Stanel,Michael C Steiner,David J. Stensel,M Stern,Isobel D. Stewart,James Stockley,Richard Kevin Stone,A Storrie,K Storton,E Stringer,Christian P Subbe,Cathie Sudlow,Z Suleiman,Charlotte Summers,C Summersgill,D Sutherland,D L Sykes,Robert Sykes,Nick P. Talbot,A L Tan,Clare J Taylor,Andrew M. Taylor,A Te,H Tedd,C J Tee,H. Tench,S Terry,S Thackray-Nocera,F Thaivalappil,D Thickett,David C. Thomas,D C Thomas,Aliki Thomas,Alfred A.R. Thompson,Teresa Thompson,T Thornton,Ryan S Thwaites,Mark J. Tobin,G F Toingson,C Tong,M Toshner,Rhian M. Touyz,K A Tripp,Elizabeth M. Tunnicliffe,E Turner,L Turtle,H Turton,R Ugwuoke,R Upthegrove,J Valabhji,K Vellore,E Wade,L V Wain,L O Wajero,S Walder,Susan P. Walker,E Wall,T Wallis,S Walmsley,S Walsh,Jill Walsh,L Watson,JM Watson,E. Watson,Carly Welch,H Welch,B. Welsh,Simon Wessely,S West,H Wheeler,V Whitehead,J Whitney,S Whittaker,B Whittam,J Wild,M Wilkins,D Wilkinson,Nicola Williams,Bryan Williams,Julie Williams,S A Williams-Howard,M Willicombe,G Willis,David Wilson,I Wilson,N Window,Miles D. Witham,R. Wolf-Roberts,F Woodhead,J Woods,Daniel G. Wootton,J Worsley,D Wraith,L Wright,C Wright,S Wright,C Xie,S Yasmin,Thomas Yates,K P Yip,B Young,S Young,A Young,A J Yousuf,A Yousuf,A Zawia,B Zhao,O. Zongo +780 more
TL;DR: In this paper, the effects of COVID-19-related hospitalisation on health and employment, to identify factors associated with recovery, and to describe recovery phenotypes were determined.
Journal ArticleDOI
Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomised, double-blind, placebo-controlled, phase 2 trial.
Phillip Monk,Richard J Marsden,Victoria Tear,Jody Brookes,Toby N Batten,Marcin Mankowski,Felicity J Gabbay,Donna E. Davies,Stephen T. Holgate,Stephen T. Holgate,Ling-Pei Ho,Tristan W Clark,Ratko Djukanovic,Tom Wilkinson,Michael G. Crooks,Davinder Dosanjh,Salman Siddiqui,Najib M. Rahman,Jacklyn A Smith,Alex Horsley,Tim Harrison,Dinesh Saralaya,Lorcan McGarvey,Alastair Watson,Edmund Foster,Adam Fleet,Dave Singh,Sophie Hemmings,Sandra Aitken,Sarah Dudley,Rona Beegan,Angela Thompson,Pedro Mb Rodrigues +32 more
TL;DR: Patients who received SNG001 had greater odds of improvement and recovered more rapidly from SARS-CoV-2 infection than patients who received placebo, providing a strong rationale for further trials.
Journal ArticleDOI
Robust SARS-CoV-2-specific T cell immunity is maintained at 6 months following primary infection.
Jianmin Zuo,Alexander C Dowell,Hayden Pearce,Kriti Verma,Heather M. Long,Jusnara Begum,Felicity Aiano,Zahin Amin-Chowdhury,Bassam Hallis,Lorrain Stapley,Ray Borrow,Ezra Linley,Shazaad Ahmad,Ben Parker,Alex Horsley,Gayatri Amirthalingam,Kevin E. Brown,Mary Ramsay,Shamez N Ladhani,Paul Moss +19 more
TL;DR: In this article, the authors analyzed the magnitude and phenotype of the SARS-CoV-2-specific T cell response in 100 donors at 6 months following infection and found that the severity of primary infection establishes a'set point' for cellular immunity.