S
Susan R. Ross
Researcher at University of Illinois at Chicago
Publications - 150
Citations - 7610
Susan R. Ross is an academic researcher from University of Illinois at Chicago. The author has contributed to research in topics: Mouse mammary tumor virus & Virus. The author has an hindex of 49, co-authored 142 publications receiving 7086 citations. Previous affiliations of Susan R. Ross include University of Texas at Austin & New York University.
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Murine retroviruses activate B cells via interaction with toll-like receptor 4.
TL;DR: These results identify retroviral proteins that interact with a mammalian toll receptor and show that direct activation by such viruses may initiate in vivo infection pathways.
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Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice
TL;DR: The results suggest that some regulatory mechanism is overridden as a consequence of transient transfection but that sequences that can control proper K14 expression are present in the construct, and that the appropriate tissue-specific and differentiation-specific expression of K14 is determined by the appropriate promoter.
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Troglitazone Action Is Independent of Adipose Tissue
Charles F. Burant,Seamus Sreenan,Ken-Ichi Hirano,Tzu Ann C. Tai,Jeffrey J. Lohmiller,John N. Lukens,Nicholas O. Davidson,Susan R. Ross,Reed A. Graves +8 more
TL;DR: The results demonstrate that insulin resistance and diabetes can occur in animals without significant adipose deposits and troglitazone can alter glucose and lipid metabolism independent of its effects on adipose tissue.
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A fat-specific enhancer is the primary determinant of gene expression for adipocyte P2 in vivo
Susan R. Ross,Reed A. Graves,Amy Greenstein,Kenneth A. Platt,Hai Lun Shyu,Barry Mellovitz,Bruce M. Spiegelman +6 more
TL;DR: It is demonstrated that the proximal-promoter binding sites for AP-1 and C/EBP are not sufficient or necessary to give adipose-tissue-specific expression in vivo, though they may play an important role in the response of this promoter to glucocorticoids.
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Transgenic mouse mammary tumor virus superantigen expression prevents viral infection.
TL;DR: It is shown that unlike their nontransgenic littermates, transgenic mice expressing high levels of an ORF protein derived from the C3H exogenous MMTV specifically delete their V beta 14+ T cells and do not become infected with this virus when it is present in their mother's milk.