S
Suzanne A. W. Fuqua
Researcher at Baylor College of Medicine
Publications - 226
Citations - 19954
Suzanne A. W. Fuqua is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Breast cancer & Estrogen receptor. The author has an hindex of 70, co-authored 222 publications receiving 18783 citations. Previous affiliations of Suzanne A. W. Fuqua include New York University & Baylor University.
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Journal ArticleDOI
Comprehensive Genomic Analysis Identifies Novel Subtypes and Targets of Triple-Negative Breast Cancer
Matthew D. Burstein,Anna Tsimelzon,Graham M. Poage,Kyle R. Covington,Alejandro Contreras,Suzanne A. W. Fuqua,Michelle I. Savage,C. Kent Osborne,Susan G. Hilsenbeck,Jenny C. Chang,Gordon B. Mills,Ching C. Lau,Powel H. Brown +12 more
TL;DR: There are four stable TNBC subtypes characterized by the expression of distinct molecular profiles that have distinct prognoses, and novel subtype-specific targets that can be targeted in the future for the effective treatment of TNBCs are identified.
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Role of the Estrogen Receptor Coactivator AIB1 (SRC-3) and HER-2/neu in Tamoxifen Resistance in Breast Cancer
C. Kent Osborne,Valerie Bardou,Torsten A. Hopp,Gary C. Chamness,Susan G. Hilsenbeck,Suzanne A. W. Fuqua,Jiemin Wong,D. Craig Allred,Gary M. Clark,Rachel Schiff +9 more
TL;DR: The antitumor activity of tamoxifen in patients with breast cancer may be determined, in part, by tumor levels of AIB1 and HER-2, which may be an important diagnostic and therapeutic target.
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Association of p53 Protein Expression With Tumor Cell Proliferation Rate and Clinical Outcome in Node-Negative Breast Cancer
D. C. Allred,Gary M. Clark,Richard M. Elledge,Suzanne A. W. Fuqua,Richard W. Brown,Gary C. Chamness,C K Osborne,William L. McGuire +7 more
TL;DR: In this article, the p53 (also known as TP53) tumor suppressor gene encodes for a nuclear phosphoprotein thought to regulate proliferation of normal cells, and the relationship between levels of mutant p53 protein expression, tumor cell proliferation rate, and clinical outcome in patients with node-negative breast cancer was investigated.
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Biological and Clinical Implications of Heat Shock Protein 27000 (Hsp27): a Review
TL;DR: Studies suggest, however, that detection of Hsp27 should not be considered to be a method for identifying hormone-responsive tumors or detecting estrogen receptors, and HSP27 and other Hsps may be active in development of resistance to stressful conditions and agents including cytotoxic drugs.
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International Union of Pharmacology. LXIV. Estrogen Receptors
Karin Dahlman-Wright,Vincent Cavaillès,Suzanne A. W. Fuqua,V. Craig Jordan,John A. Katzenellenbogen,Kenneth S. Korach,Adriana Maggi,Masami Muramatsu,Malcolm G. Parker,Jan-Åke Gustafsson +9 more
TL;DR: Estrogen receptors (ERs) are ligand-activated transcription factors that belong to the nuclear hormone receptor superfamily and have shown the ability to bind 17β-estradiol.