S
Sven Mahner
Researcher at Ludwig Maximilian University of Munich
Publications - 545
Citations - 12728
Sven Mahner is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Ovarian cancer & Medicine. The author has an hindex of 46, co-authored 439 publications receiving 9126 citations. Previous affiliations of Sven Mahner include Charité & University of Hamburg.
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Journal ArticleDOI
Improved systemic treatment for early breast cancer improves cure rates, modifies metastatic pattern and shortens post-metastatic survival: 35-year results from the Munich Cancer Registry
Dieter Hölzel,Renate Eckel,Ingo Bauerfeind,B. Baier,Thomas L. Beck,Michael Braun,Johannes Ettl,Ulrich Hamann,Marion Kiechle,Sven Mahner,Christian Schindlbeck,Johann de Waal,Nadia Harbeck,Jutta Engel +13 more
TL;DR: Over the past three decades, ATHs have dramatically improved patient survival after BC diagnosis—most likely, by eradicating prevalent micro-METs; as a result, the MET pattern has changed.
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EGFR gene copy number increase in vulvar carcinomas is linked with poor clinical outcome
Linn Woelber,Stephan Hess,H Bohlken,Pierre Tennstedt,Christine Eulenburg,Ronald Simon,Friederike Gieseking,Fritz Jaenicke,Sven Mahner,Matthias Choschzick +9 more
TL;DR: EGFR copy number aberrations are connected to other gene amplifications and probably define an human papillomaviruses-independent pathway in the development of vulvar carcinomas, and support the potential utility of EGFR inhibitors as a therapeutic alternative in a subset of vul var carcinomas.
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Efficacy and safety of niraparib as maintenance treatment in older patients (≥ 70 years) with recurrent ovarian cancer: Results from the ENGOT-OV16/NOVA trial
Michel Fabbro,Kathleen N. Moore,Anne Dørum,Anna V. Tinker,Sven Mahner,Isabel Bover,Susana Banerjee,Germana Tognon,Frédéric Goffin,Ronnie Shapira-Frommer,Robert M. Wenham,Kristina Hellman,Diane Provencher,Philipp Harter,Isabel Palacio Vázquez,Philippe Follana,Mario Javier Pineda,Mansoor Raza Mirza,Sebastien Hazard,Ursula A. Matulonis +19 more
TL;DR: For patients ≥70 years of age receiving niraparib as maintenance treatment in the ENGOT-OV16/NOVA trial, PFS benefits and incidence of any grade or serious treatment-emergent AEs were comparable to results in the younger population.
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A combined blood based gene expression and plasma protein abundance signature for diagnosis of epithelial ovarian cancer - a study of the OVCAD consortium
Dietmar Pils,Dietmar Pils,Dan Tong,Gudrun Hager,Eva Obermayr,Stefanie Aust,Georg Heinze,Maria Kohl,Eva Schuster,Andrea Wolf,Jalid Sehouli,Ioana Braicu,Ignace Vergote,Toon Van Gorp,Sven Mahner,Nicole Concin,Paul Speiser,Robert Zeillinger,Robert Zeillinger +18 more
TL;DR: The combination of gene expression and plasma protein based blood derived biomarkers in one diagnostic model increases the sensitivity and the specificity significantly and may allow earlier diagnosis of epithelial ovarian cancer.
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The Risk of Contralateral Non-sentinel Metastasis in Patients with Primary Vulvar Cancer and Unilaterally Positive Sentinel Node
Linn Woelber,Christine Eulenburg,Donata Grimm,Fabian Trillsch,Inga Bohlmann,Eike Burandt,J. Dieckmann,Susanne Klutmann,Barbara Schmalfeldt,Sven Mahner,Katharina Prieske +10 more
TL;DR: The risk of contralateral non-SLN metastasis is unclear in patients with primary vulvar cancer and bilateral sentinel lymph node (SLN) biopsy, even in cases with only unilaterally positive SLN as discussed by the authors.