S
Sven Mahner
Researcher at Ludwig Maximilian University of Munich
Publications - 545
Citations - 12728
Sven Mahner is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Ovarian cancer & Medicine. The author has an hindex of 46, co-authored 439 publications receiving 9126 citations. Previous affiliations of Sven Mahner include Charité & University of Hamburg.
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Journal ArticleDOI
Clinical management of primary vulvar cancer.
Linn Woelber,Lilli Kock,Friederike Gieseking,Cordula Petersen,Fabian Trillsch,Matthias Choschzick,Fritz Jaenicke,Sven Mahner +7 more
TL;DR: Criteria for the indication and performance of chemo/radiotherapy of the vulva/groins/pelvis are still not fully established and vary between different countries and institutions due to the low level of evidence.
Journal ArticleDOI
Bevacizumab may differentially improve ovarian cancer outcome in patients with proliferative and mesenchymal molecular subtypes
Stefan Kommoss,Boris Winterhoff,Boris Winterhoff,Ann L. Oberg,Gottfried E. Konecny,Chen Wang,Shaun M. Riska,Jian-Bing Fan,Matthew J. Maurer,Craig April,Viji Shridhar,Friedrich Kommoss,Andreas du Bois,Felix Hilpert,Sven Mahner,Klaus Baumann,W. Schroeder,Alexander Burges,Ulrich Canzler,Jeremy Chien,Andrew C. Embleton,Mahesh K. B. Parmar,Richard Kaplan,Timothy J. Perren,Lynn C. Hartmann,Ellen L. Goode,Sean C. Dowdy,Jacobus Pfisterer +27 more
TL;DR: Validation of the findings in an independent cohort could enable the use of bevacizumab for those patients most likely to benefit, thereby reducing side effects and healthcare cost.
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LION: Lymphadenectomy in ovarian neoplasms—A prospective randomized AGO study group led gynecologic cancer intergroup trial.
Philipp Harter,Jalid Sehouli,Domenica Lorusso,Alexander Reuss,Ignace Vergote,Christian Marth,Jae Weon Kim,Francesco Raspagliesi,B Lampe,Fabio Landoni,Werner Meier,David Cibula,Alexander Mustea,Sven Mahner,Ingo B. Runnebaum,Barbara Schmalfeldt,Alexander Burges,Rainer Kimmig,Uwe Wagner,Andreas du Bois +19 more
TL;DR: A prospective randomized trial including patients with newly diagnosed AOC FIGO IIB-IV with macroscopic complete resection and pre- and intra-operatively clinical negative LN were randomized intra- operatively to LNE versus no-LNE.
Journal ArticleDOI
Gynecologic Cancer InterGroup (GCIG) Consensus Review for Endometrial Stromal Sarcoma
Frédéric Amant,Anne Floquet,Michael Friedlander,Gunnar B. Kristensen,Sven Mahner,Eun Ji Nam,Matthew A. Powell,Isabelle Ray-Coquard,Nadeem Siddiqui,Peter Sykes,Anneke M. Westermann,Beatrice Seddon +11 more
TL;DR: The data support the current practice to administer adjuvant hormonal treatment, although several questions remain, such as optimal doses, regimens (progestins or aromatase inhibitors) and duration of therapy.
Journal ArticleDOI
BRCA1 gene promoter methylation status in high-grade serous ovarian cancer patients--a study of the tumour Bank ovarian cancer (TOC) and ovarian cancer diagnosis consortium (OVCAD).
Ilary Ruscito,Ilary Ruscito,Desislava Dimitrova,Ines Vasconcelos,K. Gellhaus,T. Schwachula,Filippo Bellati,Robert Zeillinger,Pierluigi Benedetti-Panici,Ignace Vergote,Sven Mahner,Dan Cacsire-Tong,Nicole Concin,Silvia Darb-Esfahani,Sandrina Lambrechts,Jalid Sehouli,S. Olek,Elena-Ioana Braicu +17 more
TL;DR: The data suggest that BRCA1 methylation determines the earlier onset of HGSOC, and supports the idea that BrcAness is not only due to mutations but also to epigenetic changes in BRCa1 promoter gene.