S
Sven Mahner
Researcher at Ludwig Maximilian University of Munich
Publications - 545
Citations - 12728
Sven Mahner is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Ovarian cancer & Medicine. The author has an hindex of 46, co-authored 439 publications receiving 9126 citations. Previous affiliations of Sven Mahner include Charité & University of Hamburg.
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Topotecan plus carboplatin versus standard therapy with paclitaxel plus carboplatin (PC) or gemcitabine plus carboplatin (GC) or pegylated liposomal doxorubicin plus carboplatin (PLDC): a randomized phase III trial of the NOGGO-AGO-Study Group-AGO Austria and GEICO-ENGOT-GCIG intergroup study (HECTOR)
Jalid Sehouli,Radoslav Chekerov,Alexander Reinthaller,Rolf Richter,Antonio González-Martín,P. Harter,Hannah Woopen,Edgar Petru,Lars Hanker,E. Keil,Pauline Wimberger,P. Klare,Christian Kurzeder,Felix Hilpert,Antje Belau,AG Zeimet,I. Bover-Barcelo,Ulrich Canzler,Sven Mahner,Werner Meier +19 more
TL;DR: The combination of carboplatin and topotecan was well tolerated with significant lower rates of severe hematological toxicities but did not improve PFS or OS in platinum-sensitive relapsed ovarian cancer compared with established standard regimens.
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PPARγ Expression is Diminished in Macrophages of Recurrent Miscarriage Placentas
Theresa M. Kolben,Elisabeth Rogatsch,Aurelia Vattai,Anna Hester,Christina Kuhn,Elisa Schmoeckel,Sven Mahner,Udo Jeschke,Thomas Kolben +8 more
TL;DR: The intermediate villous trophoblast revealed a significantly lower PPARγ expression in spontaneous and recurrent abortion and in maternal macrophages of the decidua, which seems to be associated with a specific inflammatory response against the fetus.
Journal ArticleDOI
8p deletion is strongly linked to poor prognosis in breast cancer
Patrick Lebok,A. Mittenzwei,M. Kluth,Cansu Özden,Billurvan Taskin,Khakan Hussein,Katharina Möller,A Hartmann,Annette Lebeau,Isabell Witzel,Sven Mahner,Linn Wölber,Fritz Jänicke,Stefan Geist,Peter Paluchowski,Christian Wilke,Uwe Heilenkötter,Ronald Simon,Guido Sauter,Luigi Terracciano,Rainer Krech,A von der Assen,Volkmar Müller,E Burandt +23 more
TL;DR: 8p deletion characterizes a subset of particularly aggressive breast cancers and appears to be highly suited for future DNA based prognostic breast cancer panels as it is easy to analyze and raises the possibility of a role for regulating genomic stability.
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Secondary Sentinel Node Biopsy After Previous Excision of the Primary Tumor in Squamous Cell Carcinoma of the Vulva
Linn Woelber,Donata Grimm,Eik Vettorazzi,Christian Wisotzki,Fabian Trillsch,Fritz Jaenicke,J. Schwarz,Matthias Choschzick,Sven Mahner +8 more
TL;DR: The results suggest that a secondary SLN procedure after previous vulvar surgery is feasible and can accurately reflect the groin status of selected patients and adjust for potential confounders did not alter the results.
Journal ArticleDOI
Serum carbonic anhydrase IX and its prognostic relevance in vulvar cancer.
Lilli Kock,Sven Mahner,Matthias Choschzick,Christine Eulenburg,Karin Milde-Langosch,J. Schwarz,Fritz Jaenicke,Volkmar Müller,Linn Woelber +8 more
TL;DR: Serum CAIX might be an easily assessable marker to stratify patients for adjuvant therapy and potentially monitor response, and elevated preoperative serum values are associated with unfavorable prognosis.