Sylvain Bartolami

TL;DR: Serial section analysis indicates that expression of the HCA is always limited to areas of the epithelium where nerve fibres are found, although the delay between the onset of innervation and the onsetof HCA expression varies from one region of the otocyst to another.

TL;DR: CSF1R blockade using GW2580 specifically inhibits SCI-induced microglia/macrophages proliferation, reduces gliosis and microcavity formations and improves fine motor recovery after incomplete SCI.

TL;DR: Dystrophic Dy2j/2j mice mimicking human peripheral neuropathy with reduced internodal lengths have decreased nuclear YAP which, when corrected, leads to longer internodes, showing a novel mechanism controlling myelin growth and nerve conduction, and provide a molecular ground for disease with short myelin segments.

TL;DR: The results suggest that the M3 receptor-induced inositol phosphate formation described in previous studies takes place in both postsynaptic (SGNs, OHCs) and presynaptic components of efferent cochlear synapses, and in cells that are not contacted by efferents in the adult cochlea (IHCs).

TL;DR: The data support the hypothesis that protein kinase activity regulates calcium-dependent processes that affect shape changes of outer hair cells, and are consistent with the involvement of the calcium/calmodulin-dependent enzyme, myosin light chain kinase, a known target of ML-9, but do not preclude the possibility of another intracellular target forML-9.