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Sylvia Colliec-Jouault

Researcher at IFREMER

Publications -  106
Citations -  3034

Sylvia Colliec-Jouault is an academic researcher from IFREMER. The author has contributed to research in topics: Fucoidan & Self-healing hydrogels. The author has an hindex of 27, co-authored 98 publications receiving 2643 citations. Previous affiliations of Sylvia Colliec-Jouault include Centre national de la recherche scientifique & Massachusetts Institute of Technology.

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A disaccharide repeat unit is the major structure in fucoidans from two species of brown algae.

TL;DR: The predominant repeating structure of a fraction of the fucoidan from Ascophyllum nodosum prepared by acid hydrolysis and centrifugal partition chromatography (LMWF) has in vitro anticoagulant activity, indicating that the above structure may be partly responsible for biological activity in the nativefucoidan.
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Marine polysaccharides: a source of bioactive molecules for cell therapy and tissue engineering.

TL;DR: The study of the biological properties of the polysaccharides from marine eukaryotes and marine prokaryotes revealed that thePolysaccharide from the marine environment could provide a valid alternative to traditional poly Saccharides such as glycosaminoglycans.
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Antiviral activities of sulfated polysaccharides isolated from Sphaerococcus coronopifolius (Rhodophytha, Gigartinales) and Boergeseniella thuyoides (Rhodophyta, Ceramiales).

TL;DR: Water-soluble sulfated polysaccharides isolated from two red algae collected on the coast of Morocco inhibited in vitro replication of the Human Immunodeficiency Virus (HIV) and suggested a direct inhibitory effect on HIV-1 replication by controlling the appearance of the new generations of virus and potential virucidal effect.
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Fucoidan a sulfated polysaccharide from brown algae is a potent modulator of connective tissue proteolysis.

TL;DR: Using tissue sections of human skin in ex vivo experiments, it is evidenced that this polysaccharide was able to minimize human leukocyte elastase activity resulting in the protection of humanskin elastic fiber network against the enzymatic proteolysis due to this serine proteinase.
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Low-molecular-weight fucoidan promotes therapeutic revascularization in a rat model of critical hindlimb ischemia.

TL;DR: LMW fucoidan potentiates FGF-2 activity, mobilizes SDF-1, and facilitates angiogenesis in a rat model, and could be of interest as an alternative for conventional treatment in critical ischemia.