S
Sylvie van der Werf
Researcher at Pasteur Institute
Publications - 235
Citations - 17249
Sylvie van der Werf is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Influenza A virus & Virus. The author has an hindex of 48, co-authored 235 publications receiving 14083 citations. Previous affiliations of Sylvie van der Werf include Centre national de la recherche scientifique & World Health Organization.
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Journal ArticleDOI
Characterizing and Comparing the Seasonality of Influenza-Like Illnesses and Invasive Pneumococcal Diseases Using Seasonal Waveforms.
Matthieu Domenech de Cellès,Hélène Arduin,Emmanuelle Varon,Cécile Souty,Pierre-Yves Boëlle,Daniel Lévy-Bruhl,Sylvie van der Werf,Sylvie van der Werf,Sylvie van der Werf,Jean-Claude Soulary,Didier Guillemot,Laurence Watier,Lulla Opatowski +12 more
TL;DR: A method to characterize seasonality by means of easily interpretable summary statistics of seasonal shape—or seasonal waveforms is developed, which is broadly applicable to diseases with unambiguous seasonality and is well‐suited to analyze spatially or temporally grouped data, which are common in epidemiology.
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Molecular surveillance for avian influenza A virus in king penguins (Aptenodytes patagonicus)
Chung-Ming Chang,Chung-Ming Chang,Camille Lebarbenchon,Michel Gauthier-Clerc,Céline Le Bohec,David Beaune,Yvon Le Maho,Sylvie van der Werf +7 more
TL;DR: The implementation of long-term surveillance in seabird populations of polar ecosystems to detect the potential introduction of exotic strains and potential existence of a local epidemiological cycle for avian influenza viruses is recommended.
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Nucleotides at the extremities of the viral RNA of influenza C virus are involved in type-specific interactions with the polymerase complex.
TL;DR: The results indicate that the nature of nucleotides 5 and 6' contribute to type-specificity and underline the importance of the base pairing between nucleotide 3' and 8' at the 5'-end of the RNA.
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Involvement of both DNA polymerases α and γ in the replication of adenovirus deoxyribonucleic acid in vitro
TL;DR: Endogenous DNA polymerase activity in the Adenovirus DNA replication complexes (RCs) was totally inhibited by dideoxythymidine triphosphate (ddTTP) at a ddTTP:dTTP ratio of about 5:100; this suggests that the functional enzyme involved was DNA polymerases α and γ.
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Biochemical characterization of poliovirus type 1 temperature-sensitive mutants.
TL;DR: Four temperature-sensitive mutants selected upon chemical mutagenesis of the poliovirus type 1 Mahoney strain showed a similar electrophoretic pattern except for the replicase and the protease of ts 247 which showed abnormal apparent molecular weights.