T
T. Krebs
Researcher at Cardiff University
Publications - 16
Citations - 352
T. Krebs is an academic researcher from Cardiff University. The author has contributed to research in topics: Medicine & Combustion. The author has an hindex of 6, co-authored 10 publications receiving 288 citations.
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Journal ArticleDOI
Particulate matter from both heavy fuel oil and diesel fuel shipping emissions show strong biological effects on human lung cells at realistic and comparable in vitro exposure conditions
Sebastian Oeder,Tamara Kanashova,Olli Sippula,Sean C. Sapcariu,Thorsten Streibel,Jose M. Arteaga-Salas,Johannes Passig,Marco Dilger,Hanns-Rudolf Paur,Christoph Schlager,Sonja Mülhopt,Silvia Diabaté,Carsten Weiss,Benjamin Stengel,Rom Rabe,Horst Harndorf,Tiina Torvela,Jorma Jokiniemi,Maija-Riitta Hirvonen,Carsten B. Schmidt-Weber,Claudia Traidl-Hoffmann,Kelly Ann Berube,Anna Julia Wlodarczyk,Zoe Cariad Prytherch,Bernhard Michalke,T. Krebs,André S. H. Prévôt,M. Kelbg,J. Tiggesbäumker,Erwin Karg,Gert Jakobi,S. Scholtes,Jürgen Schnelle-Kreis,Jutta Lintelmann,Georg Matuschek,Martin Sklorz,Sophie Klingbeil,Jürgen Orasche,P. Richthammer,L. Müller,M. Elsasser,Ahmed A. Reda,Thomas Gröger,Benedikt A. Weggler,Theo Schwemer,Hendryk Czech,Christopher P. Rüger,Gülcin Abbaszade,Christian Radischat,Karsten Hiller,Jeroen Buters,Gunnar Dittmar,Ralf Zimmermann +52 more
TL;DR: Exhaust fumes from a ship engine running on either common heavy fuel oil (HFO) or cleaner-burning diesel fuel (DF) influenced several essential pathways of lung cell metabolism more strongly than particles from the unrefined fuel HFO, which might be attributable to a higher soot content in DF.
Particulate Matter from Both Heavy Fuel Oil and Diesel Fuel Shipping Emissions Show Strong Biological Effects on Human Lung Cells at Realistic and Comparable In Vitro Exposure Conditions
Sebastian Oeder,Tamara Kanashova,Olli Sippula,Sean C. Sapcariu,Thorsten Streibel,Jose M. Arteaga-Salas,Johannes Passig,Marco Dilger,Hanns-Rudolf Paur,Christoph Schlager,Sonja Mülhopt,Silvia Diabaté,Carsten Weiss,Benjamin Stengel,Rom Rabe,Horst Harndorf,Tiina Torvela,Jorma Jokiniemi,Maija-Riitta Hirvonen,Carsten B. Schmidt-Weber,Claudia Traidl-Hoffmann,Kelly Ann Berube,Anna Julia Wlodarczyk,Zoe Cariad Prytherch,Bernhard Michalke,T. Krebs,André S. H. Prévôt,M. Kelbg,J. Tiggesbäumker,Erwin Karg,Gert Jakobi,S. Scholtes,Jürgen Schnelle-Kreis,Jutta Lintelmann,Georg Matuschek,Martin Sklorz,Sophie Klingbeil,Jürgen Orasche,P. Richthammer,L. Müller,M. Elsasser,Ahmed A. Reda,Thomas Gröger,Benedikt A. Weggler,Theo Schwemer,Hendryk Czech,Christopher P. Rüger,Gülcin Abbaszade,Christian Radischat,Karsten Hiller,Jeroen Buters,Gunnar Dittmar,Ralf Zimmermann +52 more
TL;DR: In this article, an air-liquid interface exposure system was used to evaluate human lung cells under realistic in vitro conditions to exhaust fumes from a ship engine running on either common heavy fuel oil (HFO) or cleaner-burning diesel fuel (DF).
Journal ArticleDOI
Toxicity testing of combustion aerosols at the air–liquid interface with a self-contained and easy-to-use exposure system
Sonja Mülhopt,Marco Dilger,Silvia Diabaté,Christoph Schlager,T. Krebs,Ralf Zimmermann,Jeroen Buters,Sebastian Oeder,Thomas Wäscher,Carsten Weiss,Hanns-Rudolf Paur +10 more
TL;DR: In this paper, a mobile and complete system providing all process technology required for cell exposure experiments at dynamic aerosol sources is presented, which is controlled by a human machine interface (HMI) with standard routines for experiments and internal testing.
Journal ArticleDOI
Lung toxicity determination by in vitro exposure at the air liquid interface with an integrated online dose measurement
TL;DR: A new online method for the first time provides an online dose measurement for in vitro experiments with nanoparticles and shows a very good correlation between the sensor signal of the quartz crystal microbalance and the deposited mass on the membranes shown by spectroscopy.
Journal ArticleDOI
Metabolic Profiling as Well as Stable Isotope Assisted Metabolic and Proteomic Analysis of RAW 264.7 Macrophages Exposed to Ship Engine Aerosol Emissions: Different Effects of Heavy Fuel Oil and Refined Diesel Fuel
Sean C. Sapcariu,Tamara Kanashova,Tamara Kanashova,M. Dilger,M. Dilger,S. Diabate,S. Diabate,Sebastian Oeder,J. Passig,C. Radischat,Jeroen Buters,Olli Sippula,Olli Sippula,Thorsten Streibel,Hanns-Rudolf Paur,Hanns-Rudolf Paur,C. Schlager,C. Schlager,Sonja Mülhopt,Sonja Mülhopt,B. Stengel,R. Rabe,H. Harndorf,T. Krebs,Erwin Karg,Thomas Gröger,Carsten Weiss,Carsten Weiss,Gunnar Dittmar,Gunnar Dittmar,Karsten Hiller,Ralf Zimmermann +31 more
TL;DR: Macrophage exposure to the gas phase of HFO leads to an induction of a pro-inflammatory metabolic and proteomic phenotype, confirming the role of inflammation and cellular stress in the response to combustion aerosols.