T. P. Corrigan

TL;DR: Exclusion of data from the one centre did not alter already published significant differences in the total incidence of deep-vein thrombosis, nor in the frequency of operative and post-operative bleeding complications observed in the control group and the heparin group.

TL;DR: In this article, the prophylactic efficacy of low-dose heparin (5000 units subcutaneously begun two hours preoperatively and continued every twelve hours for seven days) was investigated in 78 " high-risk " patients over the age of forty undergoing major surgery.

TL;DR: Data exclusion did not significantly alter the total incidence of deep-vein thrombosis nor of bleeding complications observed in both groups postoperatively, and none of the heparin-treated subjects died from postoperative pulmonary embolism.

TL;DR: Phlebography was of considerable help in deciding whether to give anticoagulant therapy and in all 7 patients where pulmonary angiography confirmed the presence of extensive emboli, phlebograms showed thrombi in the peripheral veins.

TL;DR: Although phenformin and ethylœstrenol produced a significant shortening of the dilute blood-clot lysis-time, there was no difference in the incidence of D.V.T. in the two groups of patients.