Taejun Wang

TL;DR: A novel class of fluorophores that can be excited at ∼900 nm under two-photon excitation conditions and emits in the red wavelength region (≥600 nm) has been disclosed and one of the dyes was developed into a fluorescent probe for amyloid-β plaques, a key biomarker of Alzheimer's disease.

TL;DR: In vivo administration of stool EVs from high fat diet (HFD)-fed mice induced insulin resistance and glucose intolerance compared to regular diet (RD) mice, and gut microbe-derived EVs derived from Pseudomonas panacis blocked the insulin signaling pathway in both skeletal muscle and adipose tissue.

TL;DR: In this paper, the donor-acceptor structure variation of the donor, amino substituent of acedan, an important two-photon dye, has been investigated to understand and enhance the poor emission behavior of dipolar dyes in aqueous media.

TL;DR: A two-photon excitable molecular probe for fluoride, developed based on a fluoride-specific desilylation reaction, is demonstrated to be useful for fluorescent imaging of fluoride ions in live zebrafish by one- photon as well as two-Photon microscopy for the first time.

TL;DR: The two-photon fluorescent probe addresses the selectivity issue by optimizing the electronic and steric interactions between biothiols and the probe, in addition to achieving very high sensitivity, fast-response, and biocompatibility and enables the endogenously produced hydrogen sulfide to be image with negligible interference in live cells.