Yonghoon Kwon

TL;DR: Results imply that AmEVs may act as a functional moiety for controlling gut permeability and that the regulation of intestinal barrier integrity can improve metabolic functions in HFD-fed mice.

TL;DR: In vivo administration of stool EVs from high fat diet (HFD)-fed mice induced insulin resistance and glucose intolerance compared to regular diet (RD) mice, and gut microbe-derived EVs derived from Pseudomonas panacis blocked the insulin signaling pathway in both skeletal muscle and adipose tissue.

TL;DR: It is found that CXCL12 is an adipocyte-derived chemotactic factor that recruits macrophages, and that it is a required factor for the establishment of obesity-induced adipose tissue inflammation and systemic insulin resistance.

TL;DR: The stability of the proposed finite difference method and the second-order convergence rate with respect to a discrete $\ell^{2}$-norm are proved.

TL;DR: This study suggests that emodin regulates glucose homeostasis in vivo by AMPK activation and that this may represent a novel therapeutic principle in the treatment of type 2 diabetic models.