Tai-Tung Yip

TL;DR: It is shown that accumulation of angiogenesis regulators in platelets of animals bearing malignant tumors exceeds significantly their concentration in plasma or serum, as well as their levels in Platelets from non-tumor-bearing animals.

TL;DR: A deregulated expression of an 8206-Da protein was observed by surfaceenhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-ToF MS) proteomic comparison of platelets from normal and tumor-bearing mice as mentioned in this paper.

TL;DR: Evidence is presented that changes in platelet-associated platelet factor-4 (PF-4) detect malignant growth across a spectrum of human cancers in mice and concludes that platelets-associated PF-4, but not its plasma counterpart, may represent a potential biomarker of early tumor presence.

TL;DR: The fact that the presence of a human tumor can now be detected at microscopic size, suggests that it may not be necessary to know the type and location of a tumor before initiating treatment, especially since it is feasible to use anti-cancer therapies of little or no toxicity.

TL;DR: It is concluded that platelet-associated PF-4, but not its plasma counterpart, may be a promising marker of early tumor growth or tumor recurrence.