T
Taixing Cui
Researcher at University of South Carolina
Publications - 114
Citations - 7170
Taixing Cui is an academic researcher from University of South Carolina. The author has contributed to research in topics: Angiotensin II & Vascular smooth muscle. The author has an hindex of 48, co-authored 103 publications receiving 6273 citations. Previous affiliations of Taixing Cui include University of Michigan & Morehouse School of Medicine.
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Journal ArticleDOI
Irisin Stimulates Browning of White Adipocytes through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase Signaling
Yuan Zhang,Rui Li,Yan Meng,Shiwu Li,William Donelan,Yan Zhao,Lei Qi,Mingxiang Zhang,Xingli Wang,Taixing Cui,Taixing Cui,Li-Jun Yang,Dongqi Tang,Dongqi Tang +13 more
TL;DR: The data suggest that irisin can potentially prevent obesity and associated type 2 diabetes by stimulating expression of WAT browning-specific genes via the p38 MAPK and ERK pathways.
Journal ArticleDOI
Nitrolinoleic acid: An endogenous peroxisome proliferator-activated receptor γ ligand
Francisco J. Schopfer,Yiming Lin,Paul R. S. Baker,Taixing Cui,Minerva Garcia-Barrio,Jifeng Zhang,Kai Chen,Yuqing E. Chen,Bruce A. Freeman +8 more
TL;DR: It is reported that LNO2 is a potent endogenous ligand for peroxisome proliferator-activated receptor γ (PPARγ) that acts within physiological concentration ranges and reveals that NO-mediated cell signaling reactions can be transduced by fatty acid nitration products and PPAR-dependent gene expression.
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Nitrated Fatty Acids: Endogenous Anti-inflammatory Signaling Mediators
Taixing Cui,Francisco J. Schopfer,Jifeng Zhang,Kai Chen,Tomonaga Ichikawa,Paul R. S. Baker,Carlos Batthyány,Balu K. Chacko,Xu Feng,Rakesh P. Patel,Anupam Agarwal,Bruce A. Freeman,Yuqing E. Chen +12 more
TL;DR: Observations indicate that nitroalkenes such as LNO2 and OA-NO2, derived from reactions of unsaturated fatty acids and oxides of nitrogen, are a class of endogenous anti-inflammatory mediators.
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Diabetic Downregulation of Nrf2 Activity via ERK Contributes to Oxidative Stress–Induced Insulin Resistance in Cardiac Cells In Vitro and In Vivo
Yi Tan,Tomonaga Ichikawa,Jinqing Li,Qiusheng Si,Huaitao Yang,Xiangbai Chen,Curtis S. Goldblatt,Colin J. Meyer,Xiaokun Li,Lu Cai,Taixing Cui +10 more
TL;DR: ERK-mediated suppression of Nrf2 activity leads to the oxidative stress–induced insulin resistance in adult cardiomyocytes and downregulated glucose utilization in the diabetic heart.
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Selective disruption of PPARγ2 impairs the development of adipose tissue and insulin sensitivity
Jifeng Zhang,Mingui Fu,Taixing Cui,Chen Xiong,Kefeng Xu,Wei Zhong,Yan Xiao,Donna Floyd,Jian Liang,En Li,Qing Song,Yuqing E. Chen +11 more
TL;DR: It is demonstrated that PPARγ2 deficiency impairs the development of adipose tissue and insulin sensitivity, and may provide a tool to study the role of PParγ2 in obesity and diabetes.