Takanori Matsuki

TL;DR: It is found that basic leucine zipper transcription factor ATF-like 2 (Batf2) has an antitumor effect through the up-regulation of IL-12 p40 in tumor-associated macrophages, which eventually induces CD8+ T-cell activation and accumulation within the tumor.

TL;DR: Standardized intensive multidrug treatment reduces disease progression and persistence in progressive Mycobacterium avium complex pulmonary disease and highlights the need for early diagnosis and treatment.

TL;DR: In this paper, a single-centred retrospective cohort study was conducted to evaluate the long-term outcomes in 295 patients with MAC-PD following first line treatment with standard (RFP, EB, clarithromycin [CAM]) or alternative (EB and CAM with or without fluoroquinolones (FQs) or RFP, CAM, and FQs).

TL;DR: This case supports the idea that the presence of ILD could increase a risk for TRALI and therefore the eligibility for PE therapy of anti-MDA5 Ab-positive RP-ILD patients should be carefully evaluated given the risk of acute lung injury.

TL;DR: NTM-PD patients who underwent adjuvant lung resection experienced overall favorable outcomes and achieved sputum culture conversion more frequently and long-term mortality may have been reduced by this procedure, and the level of GPL core antibody was shown to be a good clinical indicator of disease activity after surgery.