T
Takao Endo
Researcher at Sapporo Medical University
Publications - 9
Citations - 1816
Takao Endo is an academic researcher from Sapporo Medical University. The author has contributed to research in topics: Regulation of gene expression & DNA methylation. The author has an hindex of 8, co-authored 9 publications receiving 1725 citations.
Papers
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Journal ArticleDOI
Appearance of enhanced tissue features in narrow-band endoscopic imaging.
Kazuhiro Gono,Takashi Obi,Masahiro Yamaguchi,Nagaaki Ohyama,Hirohisa Machida,Yasushi Sano,Shigeaki Yoshida,Yasuo Hamamoto,Takao Endo +8 more
TL;DR: The results of clinical tests in colonoscopy and esophagoscopy indicated that NBI will be useful as a supporting method for observation of the endoscopic findings of early cancer.
Journal ArticleDOI
Endoscopic observation of tissue by narrowband illumination
Kazuhiro Gono,Kenji Yamazaki,Nobuyuki Doguchi,Tetsuo Nonami,Takashi Obi,Masahiro Yamaguchi,Nagaaki Ohyama,Hirohisa Machida,Yasushi Sano,Shigeaki Yoshida,Yasuo Hamamoto,Takao Endo +11 more
TL;DR: A new illumination method for a medical endoscope: narrow band imaging (NBI), in which the spectral bandwidth of the filtered light is narrowed, which has been shown that NBI can enhance the capillary pattern and the crypt pattern on the mucosa.
Journal ArticleDOI
Usefulness of narrow-band imaging endoscopy for diagnosis of Barrett's esophagus
TL;DR: Magnifying endoscopy by NBI is more useful than conventional magnifying endoscopeopy for the diagnosis of Barrett’s esophagus and the relationship between the endoscopic and histopathologic diagnoses was more accurate by N BI endoscopes than by conventional endoscope.
Journal Article
Epigenetic inactivation of CHFR and sensitivity to microtubule inhibitors in gastric cancer.
Ayumi Satoh,Minoru Toyota,Fumio Itoh,Yasushi Sasaki,Hiromu Suzuki,Kazuhiro Ogi,Takefumi Kikuchi,Hiroaki Mita,Toshiharu Yamashita,Takashi Kojima,Masanobu Kusano,Masahiro Fujita,Masao Hosokawa,Takao Endo,Takashi Tokino,Kohzoh Imai +15 more
TL;DR: By affecting mitotic checkpoint function, CHFR inactivation likely plays a key role in tumorigenesis in gastric cancer, and the aberrant methylation of CHFR appears to be a good molecular marker with which to predict the sensitivity of gastric cancers to microtubule inhibitors.
Journal Article
Aberrant Methylation and Silencing of the BNIP3 Gene in Colorectal and Gastric Cancer
Masafumi Murai,Minoru Toyota,Hiromu Suzuki,Ayumi Satoh,Yasushi Sasaki,Kimishige Akino,Masako Ueno,Fumihiko Takahashi,Masanobu Kusano,Hiroaki Mita,Kazuyoshi Yanagihara,Takao Endo,Yuji Hinoda,Takashi Tokino,Kohzoh Imai +14 more
TL;DR: In this paper, the expression and DNA methylation status of BNIP3 gene in a panel of colorectal and gastric cancer cell lines were examined, and it was found that methylation of the 5' CpG island was closely correlated with silencing the gene.