T
Takeji Takamura-Enya
Researcher at Kanagawa Institute of Technology
Publications - 54
Citations - 1205
Takeji Takamura-Enya is an academic researcher from Kanagawa Institute of Technology. The author has contributed to research in topics: DNA adduct & DNA. The author has an hindex of 19, co-authored 52 publications receiving 1078 citations. Previous affiliations of Takeji Takamura-Enya include Kyoto Pharmaceutical University & National Cancer Research Institute.
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Journal ArticleDOI
Frequent hypomethylation in multiple promoter CpG islands is associated with global hypomethylation, but not with frequent promoter hypermethylation
Atsushi Kaneda,Tetsuya Tsukamoto,Takeji Takamura-Enya,Naoko Watanabe,Michio Kaminishi,Takashi Sugimura,Masae Tatematsu,Toshikazu Ushijima +7 more
TL;DR: Experimental evidence is presented that frequent hypomethylation of normally methylated promoter CGIs is associated with global hypometHylation, and that these hypometrichylations occur independently of frequent promoter CGI hypermethylation.
Journal ArticleDOI
Mono(ADP-ribosyl)ation of 2′-deoxyguanosine residue in DNA by an apoptosis-inducing protein, pierisin-1, from cabbage butterfly
Takeji Takamura-Enya,Masahiko Watanabe,Yukari Totsuka,Takashi Kanazawa,Yuko Matsushima-Hibiya,Kotaro Koyama,Takashi Sugimura,Keiji Wakabayashi +7 more
TL;DR: The present studies were designed to identify the target molecule for ADP-ribosylation by pierisin-1 in the presence of β-[adenylate-32P]NAD, and it was found DNA as the acceptor, but not protein as is the case with other bacteria-derivedADP- ribosylating toxins.
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Identification of three major DNA adducts formed by the carcinogenic air pollutant 3-nitrobenzanthrone in rat lung at the C8 and N2 position of guanine and at the N6 position of adenine.
Volker M. Arlt,Heinz H. Schmeiser,Martin R. Osborne,Masanobu Kawanishi,Takaharu Kanno,Takashi Yagi,David H. Phillips,Takeji Takamura-Enya +7 more
TL;DR: In this article, 3-NBA-derived DNA adducts were detected in rodent tissues by 32P-postlabeling, all of which are derived from reductive metabolites of 3-NB bound to purine bases.
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Detection of Genistein as an Estrogenic Contaminant of River Water in Osaka
Masanobu Kawanishi,Takeji Takamura-Enya,Rahyani Ermawati,Chiaki Shimohara,Michiyo Sakamoto,Kazuki Matsukawa,Tomonari Matsuda,Tsuyoshi Murahashi,Saburo Matsui,Keiji Wakabayashi,Tetsushi Watanabe,H Yutaka Tashiro,Takashi Yagi +12 more
TL;DR: Analysis of a fraction with estrogenic activity by liquid chromatography-mass spectrometry (LC-MS) provided evidence that the activity in the water sample resulted from the presence of genistein, an isoflavone compound of plant origin.
Journal ArticleDOI
Alu and Satα hypomethylation in Helicobacter pylori-infected gastric mucosae.
Takeichi Yoshida,Satoshi Yamashita,Takeji Takamura-Enya,Tohru Niwa,Takayuki Ando,Shotaro Enomoto,Takao Maekita,Kazuyuki Nakazawa,Masae Tatematsu,Masao Ichinose,Toshikazu Ushijima +10 more
TL;DR: It is shown that Alu and Satα hypomethylation is induced in gastric mucosae by H. pylori infection during gastric carcinogenesis, possibly in different target cells, and that global hypomethalation is not always present in human gastric cancers.