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Takuya Fujita
Researcher at Osaka University
Publications - 3
Citations - 4869
Takuya Fujita is an academic researcher from Osaka University. The author has contributed to research in topics: Adiponectin & Insulin resistance. The author has an hindex of 3, co-authored 3 publications receiving 4439 citations.
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Journal ArticleDOI
Increased oxidative stress in obesity and its impact on metabolic syndrome
Shigetada Furukawa,Takuya Fujita,Michio Shimabukuro,Masanori Iwaki,Yukio Yamada,Yoshimitsu Nakajima,Osamu Nakayama,Makoto Makishima,Morihiro Matsuda,Iichiro Shimomura +9 more
TL;DR: It is suggested that increased oxidative stress in accumulated fat is an early instigator of metabolic syndrome and that the redox state in adipose tissue is a potentially useful therapeutic target for obesity-associated metabolic syndrome.
Journal ArticleDOI
Long-term treatment with the Na+-glucose cotransporter inhibitor T-1095 causes sustained improvement in hyperglycemia and prevents diabetic neuropathy in Goto-Kakizaki Rats.
Kiichiro Ueta,Tomomi Ishihara,Yukio Matsumoto,Akira Oku,Masao Nawano,Takuya Fujita,Akira Saito,Kenji Arakawa +7 more
TL;DR: Sustained improvement of hyperglycemia and prevention of diabetic neuropathy by the T-1095-treatment provide further support the use of SGLT inhibitors for the treatment of diabetes.
Journal ArticleDOI
Glucosamine induces lipid accumulation and adipogenic change in C2C12 myoblasts
Takuya Fujita,Shigetada Furukawa,Kentaro Morita,Tomomi Ishihara,Masaharu Shiotani,Yasuaki Matsushita,Morihiro Matsuda,Iichiro Shimomura,Iichiro Shimomura +8 more
TL;DR: The content of uridine-5'-diphospho-N-acetylglucosamine, the end product of the HBP, was elevated in skeletal muscle of obese diabetic KKA(y) mice, compared with control mice, providing a possible explanation of hyperglycemia-induced insulin resistance in skeletal muscles.