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Tamar Amit

Researcher at Technion – Israel Institute of Technology

Publications -  161
Citations -  10263

Tamar Amit is an academic researcher from Technion – Israel Institute of Technology. The author has contributed to research in topics: Neuroprotection & Rasagiline. The author has an hindex of 55, co-authored 160 publications receiving 9649 citations. Previous affiliations of Tamar Amit include Rappaport Faculty of Medicine & Soroka Medical Center.

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Neurological mechanisms of green tea polyphenols in Alzheimer's and Parkinson's diseases

Orly Weinreb, +3 more
- 01 Sep 2004 - 
TL;DR: Green tea polyphenols are now being considered as therapeutic agents in well controlled epidemiological studies, aimed to alter brain aging processes and to serve as possible neuroprotective agents in progressive neurodegenerative disorders such as Parkinson's and Alzheimer's diseases.
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Involvement of protein kinase C activation and cell survival/ cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action.

Yona Levites, +3 more
- 23 Aug 2002 - 
TL;DR: The results suggest that the neuroprotective mechanism of EGCG against oxidative stress-induced cell death includes stimulation of PKC and modulation of cell survival/cell cycle genes.
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Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3-gallate.

Yona Levites, +3 more
- 01 May 2003 - 
TL;DR: EGCG has protective effects against Aβ‐induced neurotoxicity and regulates secretory processing of non‐amyloidogenic APP via PKC pathway and is not only able to protect, but it can rescue PC12 cells against the β‐ameloid (Aβ) toxicity in a dose‐dependent manner.
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Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (-)-epigallocatechin-3-gallate: implications for neurodegenerative diseases.

Silvia Mandel, +3 more
- 01 Mar 2004 - 
TL;DR: Both experimental and epidemiological evidence demonstrate that flavonoid polyphenols, particularly from green tea and blueberries, improve age‐related cognitive decline and are neuroprotective in models of PD, AD and cerebral ischemia/reperfusion injuries.
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Multifunctional activities of green tea catechins in neuroprotection. Modulation of cell survival genes, iron-dependent oxidative stress and PKC signaling pathway.

Silvia Mandel, +6 more
- 01 Jan 2005 - 
TL;DR: This review will focus on the multifunctional properties of green tea and its major component (–)-epigallocatechin-3-gallate (EGCG) and their ability to induce neuroprotection and neurorescue in vitro and in vivo and their transitional metal chelating property and inhibition of oxidative stress.