T
Tao Chen
Researcher at Fourth Military Medical University
Publications - 128
Citations - 11519
Tao Chen is an academic researcher from Fourth Military Medical University. The author has contributed to research in topics: Long-term potentiation & Excitatory postsynaptic potential. The author has an hindex of 36, co-authored 111 publications receiving 8564 citations. Previous affiliations of Tao Chen include Xi'an Jiaotong University & UPRRP College of Natural Sciences.
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Edonerpic maleate regulates glutamate receptors through CRMP2- and Arc-mediated mechanisms in response to brain trauma
TL;DR: In this article , the effect of edonerpic maleate on NMDA receptor expression was mediated by collapsing response mediator protein 2 (CRMP2) and postsynaptic protein Arc.
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Controlled Decompression Alleviates Brain Injury via Attenuating Oxidative Damage and Neuroinflammation in Acute Intracranial Hypertension
Chonghui Zhang,Xiao Qian,Jie-jing Zheng,Puente-Muńoz Ai,Xinyi Cao,Xiaofei Pan,Tao Chen,Yuhai Wang +7 more
TL;DR: It is demonstrated that controlled decompression could attenuate oxidative damage and inflammatory responses, downregulate UCH-L1 and GFAP levels, and contribute to an improved neuroprotective effect compared with RDC.
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Proanthocyanidins Inhibit the Transmission of Spinal Pain Information Through a Presynaptic Mechanism in a Mouse Inflammatory Pain Model
Hongwei Fan,Zhenyu Wu,Dayu Zhu,Jun-Xiang Gu,Mang Xu,Ming-Zhe Zhang,H. Duan,Yun-Qing Li,Tao Chen +8 more
TL;DR: In summary, intrathecal injection of procyanidin induces an obvious anti-inflammatory pain effect in mice by inhibiting peripheral excitatory inputs to spinal neurons that send nociceptive information to supraspinal areas.
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Enkephalinergic Circuit Involved in Nociceptive Modulation in the Spinal Dorsal Horn.
Yang Bai,Meng-Ying Li,Jiang-Bo Ma,Jia-Ni Li,Xiao-Yu Teng,Ying-Biao Chen,Jun-Bin Yin,Jing Huang,Jing Chen,Ting Zhang,Xin-Tong Qiu,Tao Chen,Hui Li,Shengxi Wu,Ya-Nan Peng,Xiang Li,Zhen-Zhen Kou,Yun-Qing Li +17 more
TL;DR: Spinal ENKergic neurons receive direct excitatory inputs from primary afferents, which might be directly recruited to release ENK under the condition of noxious stimuli; ENK could inhibit the glutamatergic transmission towards projecting neurons via presynaptic and postsynaptic DORs.
Journal Article
The functions of liver natural killer cells in murine fulminant hepatitis induced by murine hepatitis virus strain 3
TL;DR: Recruited NK cells remarkably express CD69, enhance cytotoxic activity and IFN gamma production, which correlate with the disease severity of fulminant viral hepatitis, are suggested.