T
Tao Jin
Researcher at University of Gothenburg
Publications - 71
Citations - 2461
Tao Jin is an academic researcher from University of Gothenburg. The author has contributed to research in topics: Staphylococcus aureus & Arthritis. The author has an hindex of 25, co-authored 57 publications receiving 1924 citations. Previous affiliations of Tao Jin include Sahlgrenska University Hospital & Purdue University.
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Journal ArticleDOI
Staphylococcus aureus Resists Human Defensins by Production of Staphylokinase, a Novel Bacterial Evasion Mechanism
TL;DR: A new property of staphylokinase is reported, its ability to induce secretion of defensins, to complex bind them and to neutralize their bactericidal effect.
Journal ArticleDOI
Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss
Akilan Krishnamurthy,Vijay Joshua,Aase Haj Hensvold,Tao Jin,M Sun,Nancy Vivar,A. Jimmy Ytterberg,A. Jimmy Ytterberg,Marianne Engström,Cátia Fernandes-Cerqueira,Khaled Amara,Malin Magnusson,Gustaf Wigerblad,Jungo Kato,Juan Miguel Jimenez-Andrade,Kerry Louise Tyson,Stephen Edward Rapecki,Karin Lundberg,Sergiu-Bogdan Catrina,Per-Johan Jakobsson,Camilla I. Svensson,Vivianne Malmström,Lars Klareskog,Heidi Wähämaa,Anca I. Catrina +24 more
TL;DR: It is suggested that IL8-dependent OC activation may constitute an early event in the initiation of the joint specific inflammation in ACPA-positive RA and novel insights are provided into the key role of citrullination and PAD enzymes during OC differentiation andACPA-induced OC activation.
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Staphylococcus aureus : Staphylokinase
TL;DR: Observations indicate that staphylokinase favours symbiosis ofStaphylococci with the host that makes it an important colonization factor, supported by sepsis studies using isogenic S. aureus strains demonstrating increased bacterial load in the absence of staphyokinase production.
Journal ArticleDOI
Linkage between endosomal escape of LNP-mRNA and loading into EVs for transport to other cells.
Marco Maugeri,Muhammad Nawaz,Alexandros Papadimitriou,Annelie Angerfors,Alessandro Camponeschi,Manli Na,Mikko Hölttä,Pia Skantze,Svante Johansson,Martina Sundqvist,Johnny Lindquist,Tomas Kjellman,Inga-Lill Mårtensson,Tao Jin,Per Sunnerhagen,Sofia Östman,Lennart Lindfors,Hadi Valadi +17 more
TL;DR: It is shown that LNP-mRNAs and ionizable lipids escape the endosomes and are re-released via extracellular vesicles which could deliver the functional mRNA to other cells.
Journal ArticleDOI
The Combination of a Tumor Necrosis Factor Inhibitor and Antibiotic Alleviates Staphylococcal Arthritis and Sepsis in Mice
Ying Fei,Wanzhong Wang,Jakub Kwiecinski,Elisabet Josefsson,Rille Pullerits,Ing-Marie Jonsson,Mattias Magnusson,Tao Jin +7 more
TL;DR: Treatment with the combination of a TNF inhibitor and an antibiotic resulted in a quicker relief of clinical arthritis in mice with septic arthritis, and it was demonstrated that anti-TNF treatment downregulates high-mobility group protein B1 in staphylococcal enterotoxin shock syndrome.