Elisabet Josefsson

TL;DR: It is suggested that ClfA is a crucial virulence determinant for septic arthritis and an excellent target for the generation of immune therapies directed against S. aureus.

TL;DR: Assayed the toxicity and adhesion of 90 MRSA (methicillin resistant S. aureus) isolates and found that while there was remarkably little variation in adhesion, toxicity varied by over an order of magnitude between isolates, suggesting different evolutionary selection pressures acting on these two traits.

TL;DR: Results clearly indicate that SpA is a virulence factor of S. aureus in murine septic arthritis and the wild-type strain gave rise to more severe arthritis and higher mortality than the isogenic spa mutant strain DU5873.

TL;DR: Data indicate a common mode of action for long chain unsaturated fatty acids that involves disruption of the cell membrane, leading to interference with energy production within the bacterial cell.

TL;DR: In this paper, the influence of estrogen on T cell-independent inflammatory responses was examined, showing that even a single injection of a low dose of estradiol (3.2 μg/ mouse) given up to 4 days prior to the administration of the phlogistic compound reduced the inflammatory response.