Tao Li

TL;DR: Findings reveal that selective neuronal deletion of Atg7 is strongly protective against neuronal death and overall brain injury occurring after HI and suggest that inhibition of HI-enhanced autophagy should be considered as a potential therapeutic target for the treatment of human newborns developing severe hypoxic-ischemic encephalopathy.

TL;DR: Brief sevoflurane exposure during critical periods of early postnatal development, although it does not seem to exert major long-term effects on brain circuitry development, can induce subtle changes in synaptic plasticity and spine density of which the physiological significance remains to be determined.

TL;DR: An overview of iron metabolism and homeostasis at the cellular level, as well as its regulation at the mRNA translation level, is provided, and the importance of iron for brain development in fetal and early life in preterm infants is emphasized.

TL;DR: This study found that irradiation-induced cell death occurred mainly in the external germinal layer (EGL) of the juvenile rat cerebellum, and Interestingly, blood-brain barrier damage and blood flow reduction was considerably more pronounced in the Cerebellum compared to other brain regions.

TL;DR: The results suggest that autophagy might be a potential target for preventing radiotherapy-induced neural stem and progenitor cell death and its associated long-term side effects.