T
Tatiana Dracheva
Researcher at National Institutes of Health
Publications - 19
Citations - 1956
Tatiana Dracheva is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Lung cancer & Adenocarcinoma. The author has an hindex of 13, co-authored 19 publications receiving 1854 citations. Previous affiliations of Tatiana Dracheva include Johns Hopkins University School of Medicine.
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Journal ArticleDOI
Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival.
Maria Teresa Landi,Tatiana Dracheva,Melissa Rotunno,Jonine D. Figueroa,Huaitian Liu,Abhijit Dasgupta,Felecia E. Mann,Junya Fukuoka,Megan Hames,Andrew W. Bergen,Sharon E. Murphy,Ping Yang,Angela Cecilia Pesatori,Dario Consonni,Pier Alberto Bertazzi,Sholom Wacholder,Joanna H. Shih,Neil E. Caporaso,Jin Jen +18 more
TL;DR: This work provides insight into the smoking-related mechanisms of lung neoplasia, and shows that the very mitotic genes known to be involved in cancer development are induced by smoking and affect survival.
Journal Article
ΔNp63α and TAp63α regulate transcription of genes with distinct biological functions in cancer and development
Guojun Wu,Shuji Nomoto,Mohammad O. Hoque,Tatiana Dracheva,Motonabu Osada,Chyi-Chia Richard Lee,Seung Myung Dong,Zhongmin Guo,Nicole Benoit,Yoram Cohen,Peggy Rechthand,Joseph A. Califano,Chul So Moon,Edward A. Ratovitski,Jin Jen,David Sidransky,Barry Trink +16 more
TL;DR: The p63 gene shows remarkable structural similarity to the p53 and p73 genes, and a survey of these genes shows that p63 can regulate a wide range of downstream gene targets with various cellular functions, including cell cycle control, stress, and signal transduction.
Journal ArticleDOI
Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.
Junya Fukuoka,Takeshi Fujii,Joanna H. Shih,Tatiana Dracheva,Daoud Meerzaman,Audrey Player,Kyeong Man Hong,Sharon Settnek,Ajay Gupta,Kenneth H. Buetow,Stephen M. Hewitt,William D. Travis,Jin Jen,Jin Jen +13 more
TL;DR: The notion that BRM andBRG1 participate in two distinct chromosome remodeling complexes that are functionally complementary and that the nuclear presence of BRM, its coexpression with nuclear BRG1, and the altered cellular localization ofBRM (M-BRM) are useful markers for non-small cell lung cancer prognosis is supported.
PatentDOI
Molecular characteristics of non-small cell lung cancer
TL;DR: In this paper, the authors used hierarchical clustering to examine gene expression profiles generated by serial analysis of gene expression (SAGE) in a total of nine normal lung epithelial cells and non-small cell lung cancers (NSCLC).
Journal Article
Oncogenic β-Catenin Is Required for Bone Morphogenetic Protein 4 Expression in Human Cancer Cells
Jung-Sik Kim,Heather Crooks,Tatiana Dracheva,Tagvor G. Nishanian,Baljit Singh,Jin Jen,Todd Waldman +6 more
TL;DR: These data identify the presence of regulatory interactions between the Wnt and BMP signaling pathways in cancer pathogenesis, providing an intriguing connection between the sporadic and inherited forms of a common human malignancy.