Tatsuji Yasuda

TL;DR: Anticardiolipin antibodies derived from the sera of individuals exhibiting the antiphospholipid syndrome directly bind to beta 2- glycoprotein I (beta 2-GPI), which is adsorbed to an oxidized polystyrene surface by irradiation with electron or gamma-ray radiation.

TL;DR: Among mevalonate metabolites, geranylgeranylated Rho small GTPase(s) promote the degradation of p27 during G1/S transition in FRTL-5 cells and are absolutely required for the elimination of p 27 followed by Cdk2 activation.

TL;DR: Results showed TBARS formed and the loss of arachidonic acid during lipid peroxidation, and that hydroxyl radical formed by the Fenton reaction were completely inhibited by ginseng extract, suggesting this antioxidant effect of ginsang may be responsible for its wide pharmacological actions in clinical practice by a free radical reaction-inhibition mechanism.

TL;DR: It is demonstrated that oxLDL forms stable and nondissociable complexes with beta2-GPI in serum, and that high serum levels of the complexes are associated with arterial thrombosis in APS.

TL;DR: To confirm the revised lipid A structure of Escherichia coli and to establish the structure responsible for its functions, biological activities of the synthetic compounds based on the presented structure of E. coli lipid A were investigated.