T
Tejasav S. Sehrawat
Researcher at Mayo Clinic
Publications - 30
Citations - 5133
Tejasav S. Sehrawat is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Alcoholic hepatitis & Medicine. The author has an hindex of 11, co-authored 24 publications receiving 1841 citations. Previous affiliations of Tejasav S. Sehrawat include Government Medical College, Thiruvananthapuram.
Papers
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Journal ArticleDOI
Post-acute COVID-19 syndrome.
Ani Nalbandian,Kartik Sehgal,Kartik Sehgal,Aakriti Gupta,Aakriti Gupta,Mahesh V. Madhavan,Claire McGroder,Jacob S. Stevens,Joshua R. Cook,Anna S. Nordvig,Daniel Shalev,Tejasav S. Sehrawat,Neha Ahluwalia,Behnood Bikdeli,Donald Dietz,Caroline Der-Nigoghossian,Nadia Liyanage-Don,Gregg F. Rosner,Elana J. Bernstein,Sumit Mohan,Akinpelumi A Beckley,David S. Seres,Toni K. Choueiri,Toni K. Choueiri,Nir Uriel,John C. Ausiello,Domenico Accili,Daniel E. Freedberg,Matthew R. Baldwin,Allan Schwartz,Daniel Brodie,Christine Kim Garcia,Mitchell S.V. Elkind,Jean M. Connors,Jean M. Connors,John P. Bilezikian,Donald W. Landry,Elaine Wan +37 more
TL;DR: A comprehensive review of the current literature on post-acute COVID-19, its pathophysiology and its organ-specific sequelae is provided in this paper, where the authors discuss relevant considerations for the multidisciplinary care of COPD survivors and propose a framework for the identification of those at high risk for COPD and their coordinated management through dedicated COPD clinics.
Journal ArticleDOI
Extrapulmonary manifestations of COVID-19.
Aakriti Gupta,Aakriti Gupta,Mahesh V. Madhavan,Kartik Sehgal,Kartik Sehgal,Nandini Nair,Shiwani Mahajan,Tejasav S. Sehrawat,Behnood Bikdeli,Behnood Bikdeli,Neha Ahluwalia,John C. Ausiello,Elaine Wan,Daniel E. Freedberg,Ajay J. Kirtane,Sahil A. Parikh,Mathew S. Maurer,Anna S. Nordvig,Domenico Accili,Joan M. Bathon,Sumit Mohan,Kenneth A. Bauer,Kenneth A. Bauer,Martin B. Leon,Harlan M. Krumholz,Nir Uriel,Mandeep R. Mehra,Mitchell S.V. Elkind,Mitchell S.V. Elkind,Gregg W. Stone,Allan Schwartz,David D. Ho,John P. Bilezikian,Donald W. Landry +33 more
TL;DR: The extrapulmonary organ-specific pathophysiology, presentations and management considerations for patients with COVID-19 are reviewed to aid clinicians and scientists in recognizing and monitoring the spectrum of manifestations, and in developing research priorities and therapeutic strategies for all organ systems involved.
Journal ArticleDOI
Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension
Moira B. Hilscher,Tejasav S. Sehrawat,Juan Pablo Arab,Zhutian Zeng,Jinhang Gao,Mengfei Liu,Enis Kostallari,Yandong Gao,Douglas A. Simonetto,Usman Yaqoob,Sheng Cao,Alexander Revzin,Arthur Beyder,Rong Wang,Patrick S. Kamath,Paul Kubes,Vijay H. Shah +16 more
TL;DR: In studies of L SECs and knockout mice, mechanosensitive angiocrine signals released by LSECs are identified which promote PHTN by recruiting sinusoidal neutrophils and promoting formation of NETs and microthrombi.
Journal ArticleDOI
An Open‐Label, Dose‐Escalation Study to Assess the Safety and Efficacy of IL‐22 Agonist F‐652 in Patients With Alcohol‐associated Hepatitis
Juan Pablo Arab,Juan Pablo Arab,Tejasav S. Sehrawat,Douglas A. Simonetto,Vikas K. Verma,Dechun Feng,Tom Tang,Kevin Dreyer,Xiaoqiang Yan,William L. Daley,Arun J. Sanyal,Naga Chalasani,Svetlana Radaeva,Liu Yang,Hugo E. Vargas,Mauricio Ibacache,Bin Gao,Gregory J. Gores,Harmeet Malhi,Patrick S. Kamath,Vijay H. Shah +20 more
TL;DR: This study aims to assess the safety and efficacy signals of F‐652 in patients with moderate and severe AH.
Journal ArticleDOI
IRE1A Stimulates Hepatocyte-Derived Extracellular Vesicles That Promote Inflammation in Mice With Steatohepatitis
Debanjali Dasgupta,Yasuhiko Nakao,Yasuhiko Nakao,Amy S. Mauer,Jill Thompson,Tejasav S. Sehrawat,Chieh Yu Liao,Anuradha Krishnan,Fabrice Lucien,Qianqian Guo,Mengfei Liu,Fei Xue,Masanori Fukushima,Tomohiro Katsumi,Aditya Bansal,Mukesh K. Pandey,Jessica L. Maiers,Timothy R. DeGrado,Samar H. Ibrahim,Alexander Revzin,Kevin D. Pavelko,Michael A. Barry,Randal J. Kaufman,Harmeet Malhi +23 more
TL;DR: In mouse hepatocytes, activated IRE1A promotes transcription of serine palmitoyltransferase genes via XBP1, resulting in ceramide biosynthesis and release of EVs, and strategies to block this pathway might be developed to reduce liver inflammation in patients with NASH.