T
Teresa Druck
Researcher at Ohio State University
Publications - 81
Citations - 7369
Teresa Druck is an academic researcher from Ohio State University. The author has contributed to research in topics: FHIT & Gene. The author has an hindex of 40, co-authored 80 publications receiving 7184 citations. Previous affiliations of Teresa Druck include Thomas Jefferson University & The Ohio State University Wexner Medical Center.
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Journal ArticleDOI
Molecular cloning of the interleukin-1 beta converting enzyme
Douglas P. Cerretti,Carl J. Kozlosky,Bruce Mosley,Nicole Nelson,Kirk P. Van Ness,Teresa A. Greenstreet,Carl J. March,Shirley R. Kronheim,Teresa Druck,Linda A. Cannizzaro,Kay Huebner,Roy A. Black +11 more
TL;DR: A complementary DNA encoding a protease that carries out this cleavage has been cloned in this paper, and the gene encoding the protease was mapped to chromosomal band 11q23, a site frequently involved in rearrangement in human cancers.
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The FHIT Gene, Spanning the Chromosome 3p14.2 Fragile Site and Renal Carcinoma–Associated t(3;8) Breakpoint, Is Abnormal in Digestive Tract Cancers
Masataka Ohta,Hiroshi Inoue,Maria Grazia Cotticelli,Kumar Kastury,Raffaele Baffa,Juan P. Palazzo,Zurab Siprashvili,Masaki Mori,Peter McCue,Teresa Druck,Carlo M. Croce,Kay Huebner +11 more
TL;DR: A 200-300 kb region of chromosome 3p14.2, including the fragile site locus FRA3B, is homozygously deleted in multiple tumor-derived cell lines, allowing identification of the human FHIT gene, a member of ther histidine triad gene family, which encodes a protein with 69% similarity to an S. pombe enzyme.
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Cloning, Characterization, and Chromosomal Localization of a Human 5-HT6 Serotonin Receptor
Ruth Kohen,Mark A. Metcalf,Naseem Khan,Teresa Druck,Kay Huebner,Jean E. Lachowicz,Herbert Y. Meltzer,David R. Sibley,Bryan L. Roth,Mark W. Hamblin,Mark W. Hamblin +10 more
TL;DR: Comparison of genomic and cDNA clones for the human 5‐HT6 receptor reveals an RsaI restriction fragment length polymorphism within the coding region, suggesting that these may be closely linked.
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Characterization of the Mammalian YAP (Yes-associated Protein) Gene and Its Role in Defining a Novel Protein Module, the WW Domain
Marius Sudol,Peer Bork,Aaron Einbond,Kumar Kastury,Teresa Druck,Massimo Negrini,Kay Huebner,David Lehman +7 more
TL;DR: CDNA cloning and characterization of the human and mouse orthologs of the chicken YAP (Yes-associated protein) gene which encodes a novel protein that binds to the SH3 (Src homology 3) domain of the Yes proto-oncogene product are reported.
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Cloning and characterization of two members of the vertebrate Dlx gene family.
Antonio Simeone,Dario Acampora,Maria Pannese,Maurizio D'Esposito,Anna Stornaiuolo,Massimo Gulisano,Antonello Mallamaci,Kumar Kastury,Teresa Druck,Kay Huebner +9 more
TL;DR: The expression pattern of these genes, together with their chromosome localization, may provide useful cues for the study of congenital disorders in which there is a combination of craniofacial and limb defects.