T
Teruo Watanabe
Researcher at Saga University
Publications - 38
Citations - 2076
Teruo Watanabe is an academic researcher from Saga University. The author has contributed to research in topics: Lipoprotein & Cholesterol. The author has an hindex of 25, co-authored 38 publications receiving 1900 citations. Previous affiliations of Teruo Watanabe include University of Tsukuba & Saga Group.
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Rabbit models for the study of human atherosclerosis: from pathophysiological mechanisms to translational medicine.
TL;DR: The features of rabbit lipoprotein metabolism and pathology of atherosclerotic lesions that make it the optimal model for human atherosclerosis disease, especially for the translational medicine are focused on.
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C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance.
Huijun Sun,Tomonari Koike,Tomonaga Ichikawa,Kinta Hatakeyama,Masashi Shiomi,Bo Zhang,Shuji Kitajima,Masatoshi Morimoto,Teruo Watanabe,Yujiro Asada,Yuqing E. Chen,Jianglin Fan +11 more
TL;DR: There is a link between plasma CRP and the degree of atherosclerosis and that inhibition of plasmaCRP may represent a therapeutic modality for the treatment of cardiovascular disease.
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Transgenic rabbits as therapeutic protein bioreactors and human disease models.
Jianglin Fan,Teruo Watanabe +1 more
TL;DR: The achievements made thus far with transgenic rabbits are introduced, with emphasis on the application of these rabbits as human disease models and live bioreactors for producing human therapeutic proteins and on the recent progress in cloned rabbits.
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Macrophage Metalloelastase Accelerates the Progression of Atherosclerosis in Transgenic Rabbits
Jingyan Liang,Enqi Liu,Ying Yu,Shuji Kitajima,Tomonari Koike,Yingji Jin,Masatoshi Morimoto,Kinta Hatakeyama,Yujiro Asada,Teruo Watanabe,Yasuyuki Sasaguri,Shigeyuki Watanabe,Jianglin Fan +12 more
TL;DR: The results suggest that macrophage-derived MMP-12 participates in the progression of atherosclerosis, and may play a pivotal role in the cascade activation of other MMPs, thereby exacerbating extracellular matrix degradation during the progress of Atherosclerosis.
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Increased Expression of Vascular Endothelial Growth Factor in Kidney Leads to Progressive Impairment of Glomerular Functions
Enqi Liu,Masatoshi Morimoto,Shuji Kitajima,Tomonari Koike,Ying Yu,Hideo Shiiki,Michio Nagata,Teruo Watanabe,Jianglin Fan +8 more
TL;DR: This study provides the first evidence that increased expression of V EGF in glomeruli directly causes the glomerular hypertrophy that is associated with proteinuria, suggesting that VEGF exerts multiple effects on the glomersular pathophysiologic processes.