T
Tetsuya Mitsudomi
Researcher at Kindai University
Publications - 583
Citations - 51959
Tetsuya Mitsudomi is an academic researcher from Kindai University. The author has contributed to research in topics: Lung cancer & Epidermal growth factor receptor. The author has an hindex of 97, co-authored 541 publications receiving 46183 citations. Previous affiliations of Tetsuya Mitsudomi include University of Occupational and Environmental Health Japan & Gunma University.
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Journal ArticleDOI
Outcomes After Hepatic and Pulmonary Metastasectomies Compared With Pulmonary Metastasectomy Alone in Patients With Colorectal Cancer Metastasis to Liver and Lungs
Norifumi Hattori,Yukihide Kanemitsu,Koji Komori,Yasuhiro Shimizu,Tsuyoshi Sano,Yoshiki Senda,Tetsuya Mitsudomi,Takayuki Fukui +7 more
TL;DR: Resection of pulmonary colorectal metastases may increase survival, however, the combination of liver and lung metastasectomies had a worse prognosis than pulmonary metastasectomy alone.
Journal ArticleDOI
Efficacy of irreversible EGFR-TKIs for the uncommon secondary resistant EGFR mutations L747S, D761Y, and T854A
Masato Chiba,Yosuke Togashi,Eri Bannno,Yoshihisa Kobayashi,Yu Nakamura,Hidetoshi Hayashi,Masato Terashima,Marco A. De Velasco,Kazuko Sakai,Yoshihiko Fujita,Tetsuya Mitsudomi,Kazuto Nishio +11 more
TL;DR: In conclusion, this work suggests that irreversible EGFR-TKIs, especially third-generation EG FR-TkIs, can be effective against uncommon secondary mutations and that switching to third- Generation EGFR -TK is could be a promising treatment strategy for patients with acquired resistance because of these uncommon secondary mutation.
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Surgical Outcomes of Lung Cancer in Patients with Combined Pulmonary Fibrosis and Emphysema
Takahiro Mimae,Kenji Suzuki,Masahiro Tsuboi,Kanji Nagai,Norihiko Ikeda,Tetsuya Mitsudomi,Hisashi Saji,Sakae Okumura,Meinoshin Okumura,Kenichi Yoshimura,Morihito Okada +10 more
TL;DR: Patients with lung cancer and CPFE had poor prognoses regardless of apparently good pulmonary function and showed quite high postoperative mortality rates, and a lower %VC that might reflect the severity of pulmonary fibrosis was associated with poor prognosis.
Journal ArticleDOI
p53 mutations in non-small-cell lung cancers occurring in individuals without a past history of active smoking.
Y. Takagi,Hirotaka Osada,Tetsuo Kuroishi,Tetsuya Mitsudomi,Masashi Kondo,T. Niimi,Shigetoyo Saji,Adi F. Gazdar,Takashi Takahashi,John D. Minna +9 more
TL;DR: Analysis of 69 non-small-cell lung cancer specimens from individuals without any history of active smoking showed absence of significant relationship between p53 mutations and age, sex, histological type or disease stage, and comparison of mutational spectra demonstrated G:C to T:A transversions to be significantly less frequent in non-smokers than in smokers.
nodules: the differences between nodules with and without growth
TL;DR: Three fourths of resected GGNs were positive for EGFR, KRAS, ALK, or HER2 mutations, and Quadruple-negative tumors were associated with a lack of GGN growth, whereas EGFR mutation-positive tumors displayed a correlation with growth.