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Thomas C. Merigan
Researcher at Stanford University
Publications - 515
Citations - 34283
Thomas C. Merigan is an academic researcher from Stanford University. The author has contributed to research in topics: Interferon & Virus. The author has an hindex of 98, co-authored 514 publications receiving 33941 citations. Previous affiliations of Thomas C. Merigan include University of Arizona & Rockefeller Institute of Government.
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Inhibition of human cytomegalovirus replication by 9-(1,3-dihydroxy-2-propoxymethyl)guanine alone and in combination with human interferons.
TL;DR: The inhibitory action of 9-(1,3-dihydroxy-2-propoxymethyl)guanine on the replication of human cytomegalovirus was studied and viral infectivity and viral DNA synthesis were reduced more than viral protein synthesis.
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Effects of interferon-alpha on human warts.
George J. Pazin,Monto Ho,Harry W. Haverkos,John A. Armstrong,Mary C. Breinig,Harry L. Wechsler,Ann M. Arvin,Thomas C. Merigan,Kari Cantell +8 more
TL;DR: Two patients with extensive warts which were stable for two years or more were treated with human Interferon-alpha to assess the ability of interferon to affect this benign tumor of viral etiology.
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Characteristics of interferon induced in vitro and in vivo by a TRIC agent.
Thomas C. Merigan,Lavelle Hanna +1 more
TL;DR: A TRIG agent (LB-1), a member of the psittacosis-LGV-trachoma group, can induce the production in vivo and in vitro of a material with antiviral activity similar to virus-induced interferon.
Journal Article
Plasma viremia in human immunodeficiency virus infection: relationship to stage of disease and antiviral treatment.
David Katzenstein,Mark Holodniy,Dennis Israelski,Sengupta S,Larry A. Mole,Jeff Bubp,Thomas C. Merigan +6 more
TL;DR: Quantitative culture of human immunodeficiency virus was performed on 121 plasma samples from 76 HIV-infected individuals to determine the sensitivity of the assay at different stages of disease and to measure the effect of antiviral therapy on plasma viremia.
Journal Article
Interferon inhibition of lymphocyte mitogenesis.
TL;DR: In this paper, the early phase of mitogenic action of Concanavalin A on lymphocytes was measured by incorporation of labelled precursors in RNA, DNA or protein, and there was no evidence for a role of cyclic AMP in the process of inhibition.