T
Thomas Johnson
Researcher at University of Lagos
Publications - 28
Citations - 1046
Thomas Johnson is an academic researcher from University of Lagos. The author has contributed to research in topics: Type 2 diabetes & Population. The author has an hindex of 20, co-authored 26 publications receiving 945 citations. Previous affiliations of Thomas Johnson include University of Cape Coast.
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Journal ArticleDOI
A Genome-Wide Search for Type 2 Diabetes Susceptibility Genes in West Africans The Africa America Diabetes Mellitus (AADM) Study
Charles N. Rotimi,Guanjie Chen,Adebowale Adeyemo,Adebowale Adeyemo,Paulette Furbert-Harris,Debra Guass,Jie Zhou,Kate Berg,Olufemi Adegoke,Albert G.B. Amoah,Samuel Owusu,Joseph Acheampong,Kofi Agyenim-Boateng,Benjamin A. Eghan,Johnnie Oli,Godfrey Okafor,Ester Ofoegbu,Babatunde Osotimehin,Fayeofori Abbiyesuku,Thomas Johnson,Theresa Rufus,Olufemi Fasanmade,Rick A. Kittles,Harold I. Daniel,Yuanxiu Chen,Georgia M. Dunston,Francis S. Collins +26 more
TL;DR: A genome-wide linkage analysis of type 2 diabetes in a cohort of 343 affected sibling pairs in West Africa, where diabetes is less common than in the U.S, found suggestive evidence of linkage in four regions on three chromosomes.
Journal ArticleDOI
Low HDL-cholesterol with normal triglyceride levels is the most common lipid pattern in West Africans and African Americans with Metabolic Syndrome: Implications for cardiovascular disease prevention
Anne E. Sumner,Jie Zhou,Ayo P. Doumatey,Omoye E. Imoisili,Albert G.B. Amoah,Joseph Acheampong,Johnnie Oli,Thomas Johnson,Clement Adebamowo,Charles N. Rotimi +9 more
TL;DR: Elevated triglyceride levels were uncommon in both WA and AA with MetSyn, and caution is warranted in diagnosing MetSyn in WA, the ancestral population of AA.
Journal ArticleDOI
In Search of Susceptibility Genes for Type 2 Diabetes in West Africa: The Design and Results of the First Phase of the AADM Study
Charles N. Rotimi,Georgia M. Dunston,Kate Berg,Omobosola Akinsete,Albert G.B. Amoah,Samuel Owusu,Joseph Acheampong,Kofi Boateng,Johnnie Oli,Godfrey Okafor,Belonwu M. Onyenekwe,Belonwu M. Onyenekwe,Babatunde Osotimehin,Babatunde Osotimehin,Fayeofori Abbiyesuku,Thomas Johnson,Olufemi Fasanmade,Paulette Furbert-Harris,Rick A. Kittles,Mirjana Vekich,Olufemi Adegoke,George E. Bonney,Francis S. Collins +22 more
TL;DR: The Africa America Diabetes Mellitus study will create a comprehensive epidemiologic and genetic resource that will facilitate a powerful genome-wide search for West African susceptibility genes to type 2 diabetes.
Journal Article
Prevalence and determinants of diabetic retinopathy and cataracts in West African type 2 diabetes patients.
Charles N. Rotimi,Harold I. Daniel,Jie Zhou,Obisesan A,Chen G,Yuanxiu Chen,Albert G.B. Amoah,Opoku,Joseph Acheampong,Kofi Agyenim-Boateng,Benjamin A. Eghan,Johnnie Oli,Godfrey Okafor,EN Ofoegbu,Babatunde Osotimehin,Fayeofori Abbiyesuku,Thomas Johnson,Olufemi Fasanmade,Ayo P. Doumatey,Aje T,Francis Collins,Georgia M. Dunston +21 more
TL;DR: The low prevalence of retinopathy and cataracts observed within the first 5 years of diagnosis of diabetes in this cohort, suggests that intensive blood glucose control may reduce the risk of the development and progression of retInopathy andCataracts.
Journal ArticleDOI
ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response.
Adebowale Adeyemo,Norann A. Zaghloul,Guanjie Chen,Ayo P. Doumatey,Carmen C. Leitch,Timothy L. Hostelley,Jessica E. Nesmith,Jie Zhou,Amy R. Bentley,Daniel Shriner,Olufemi Fasanmade,Godfrey Okafor,Benjamin A. Eghan,Kofi Agyenim-Boateng,Settara C. Chandrasekharappa,Jokotade Adeleye,William Balogun,Samuel Owusu,Albert G.B. Amoah,Joseph Acheampong,Thomas Johnson,Johnnie Oli,Clement Adebamowo,South Africa Zulu Type Diabetes Case-Control Study,Francis S. Collins,Georgia M. Dunston,Charles N. Rotimi +26 more
TL;DR: A genome-wide analysis of type 2 diabetes (T2D) in sub-Saharan Africans, an understudied ancestral group, is reported and a locus, ZRANB3, is identified that is specific for this population is identified.