Thomas M. Gøgsig

TL;DR: A new efficient protocol for the nickel-catalyzed Heck reaction of aryl triflates with vinyl ethers is presented, representing a practical and more sustainable alternative to the conventional regioselective arylation of Vinyl ethers.

TL;DR: General reaction conditions were developed for the Pd(0)-catalyzed Suzuki-Miyaura coupling reaction of aryl boronic acids with a simple electrophilic vinylation reagent, vinyl tosylate, providing access to styrene derivatives in good yields.

TL;DR: With certain members of this class of alkenyl phosphates either the migrated or nonmigrated Heck products may be preferentially synthesized by selection of the phosphine ligand, as well as competition experiments between an unactivated aryl chloride and a vinyl phosphate with a palladium catalyst possessing either X-Phos or P(t-Bu)3 as ligand.

TL;DR: Application to isotope labeling, incorporating (13)CO, was further established and an effective exploitation of the hazardous CO gas is obtained affording chalcone derivatives in good yields.

TL;DR: Employment of heteroaromatic tosylates and phosphates as suitable electrophiles in iron-catalyzed cross-coupling reactions with alkyl Grignard reagents is reported.