Thomas M. Jarrett

TL;DR: It is found that removal of NR3A is required to develop strong NMDAR currents, full expression of long-term synaptic plasticity, a mature synaptic organization characterized by more synapses and larger postsynaptic densities, and the ability to form long- term memories.

TL;DR: Disruption in MB in dams and their 1st-generation offspring is reported, attributable to main and interaction effects of maternal treatment, litter PDE, and rearing experience.

TL;DR: No increase in maternal aggression following chronic gestational treatment and significantly lower levels of aggression in intermittently treated dams on postpartum day eight are reported, with no significant effects in either group on post partum day 12.

TL;DR: The results suggest that dam treatment with ethanol and nicotine can somewhat negatively affect the early rearing environment, and that prenatal exposure to both of these drugs results in drinking behavior differing from what would be expected from either drug alone.

TL;DR: Cocaine-induced alterations in OT system dynamics (levels, receptors, production, and/or release) may mediate heightened maternal aggression following cocaine treatment, but the exact mechanisms through which cocaine impacts the OT system have not yet been determined.