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Icíar P. López
Researcher at University of Navarra
Publications - 37
Citations - 979
Icíar P. López is an academic researcher from University of Navarra. The author has contributed to research in topics: Insulin-like growth factor 1 receptor & Medicine. The author has an hindex of 15, co-authored 29 publications receiving 801 citations. Previous affiliations of Icíar P. López include University of Barcelona.
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Journal ArticleDOI
DNA microarray analysis of genes differentially expressed in diet-induced (cafeteria) obese rats.
Icíar P. López,Amelia Marti,Fermín I. Milagro,Maria Angeles Zulet,María J. Moreno-Aliaga,J. Alfredo Martínez,Carlos de Miguel +6 more
TL;DR: This study showed that in diet-induced obesity, the expression levels of some important genes implicated in lipid metabolism were up-regulated, whereas those related to redox and stress protein were down-regulated in obese animals compared with control.
Journal ArticleDOI
Downregulation of NR3A-Containing NMDARs Is Required for Synapse Maturation and Memory Consolidation
Adam C. Roberts,Javier Díez-García,Ramona M. Rodriguiz,Icíar P. López,Rafael Luján,Rebeca Martínez-Turrillas,Esther Picó,Maile A. Henson,Danilo Bernardo,Thomas M. Jarrett,Dallis J. Clendeninn,Laura López-Mascaraque,Guoping Feng,Donald C. Lo,John F. Wesseling,William C. Wetsel,Benjamin D. Philpot,Isabel Pérez-Otaño +17 more
TL;DR: It is found that removal of NR3A is required to develop strong NMDAR currents, full expression of long-term synaptic plasticity, a mature synaptic organization characterized by more synapses and larger postsynaptic densities, and the ability to form long- term memories.
Journal ArticleDOI
Expression of the mRNA coding the cannabinoid receptor 2 in the pallidal complex of Macaca fascicularis.
José L. Lanciego,José L. Lanciego,Pedro Barroso-Chinea,Pedro Barroso-Chinea,Alberto J. Rico,Alberto J. Rico,Lorena Conte-Perales,Lorena Conte-Perales,Lucía Callén,Elvira Roda,Elvira Roda,Virginia Gómez-Bautista,Virginia Gómez-Bautista,Icíar P. López,Icíar P. López,Carmen Lluis,Jose L. Labandeira-Garcia,Jose L. Labandeira-Garcia,Rafael Franco,Rafael Franco +19 more
TL;DR: The presence of the messenger coding CB2-Rs within the pallidal complex highlights their consideration as potential targets for the treatment of movement disorders of basal ganglia origin.
Journal ArticleDOI
Changes to interneuron-driven striatal microcircuits in a rat model of Parkinson's disease.
Pascal Salin,Icíar P. López,Philippe Kachidian,Pedro Barroso-Chinea,Alberto J. Rico,Virginia Gómez-Bautista,Patrice Coulon,Lydia Kerkerian-Le Goff,José L. Lanciego +8 more
TL;DR: These data provide the first evidence of synaptic reorganization between striatal interneurons and projection neurons, notably a switch of cholinergic innervation onto striatopallidal neurons, which could contribute to imbalanced striatal outflow in parkinsonian state.
Journal ArticleDOI
Gene expression changes in rat white adipose tissue after a high-fat diet determined by differential display.
Icíar P. López,Fermín I. Milagro,Amelia Marti,María J. Moreno-Aliaga,José Alfredo Martínez,C. de Miguel +5 more
TL;DR: The differences in gene expression pattern of visceral white adipose tissue between control and high-fat-fed rats were compared using the mRNA differential display methodology and showed eight genes upregulated and four genes downregulated.