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Tibor Füle

Researcher at Semmelweis University

Publications -  16
Citations -  664

Tibor Füle is an academic researcher from Semmelweis University. The author has contributed to research in topics: Preeclampsia & HELLP syndrome. The author has an hindex of 12, co-authored 16 publications receiving 594 citations.

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Microarray profiling reveals that placental transcriptomes of early-onset HELLP syndrome and preeclampsia are similar.

TL;DR: High-throughput transcriptional and tissue microarray expression profiling revealed that placental transcriptomes of early-onset preeclampsia and HELLP syndrome largely overlap, underlying a potential common cause and pathophysiologic processes in these syndromes.
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Placental protein 13 (galectin-13) has decreased placental expression but increased shedding and maternal serum concentrations in patients presenting with preterm pre-eclampsia and HELLP syndrome

TL;DR: Third trimester maternal serum PP13 concentration increased with gestational age in normal pregnancies, and it was significantly higher in women presenting with preterm pre-eclampsia and hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome.
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Clinical significance of genetic alterations and expression of epidermal growth factor receptor (EGFR) in head and neck squamous cell carcinomas

TL;DR: It is found that increased EGFR protein levels and gene copy numbers (not gene amplification alone) have prognostic significance in the investigated HNSCC patient population, however, the relatively high incidence of the EGFR-vIII mutant form warrants careful therapeutic decision-making when choosing between different anti-EGFR treatment options.
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Deletion analysis of tumor and urinary DNA to detect bladder cancer: Urine supernatant versus urine sediment

TL;DR: To evaluate which fraction (supernatant or sediment) provides more reliable results in detecting tumors, blood, urine and tumor samples taken from 80 individuals were analyzed by using 12 microsatellite markers mapped on 6 chromosomes.
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Genomic instability in giant cell tumor of bone. A study of 52 cases using DNA ploidy, relocalization FISH, and array-CGH analysis.

TL;DR: The results show that ploidy determination combined with FISH analysis may help predicting recurrence potential of GCTB and suggest that chromosomal abnormalities superimposed on telomeric associations could be responsible for an aggressive clinical course.