T
Tim D. Oury
Researcher at University of Pittsburgh
Publications - 164
Citations - 11438
Tim D. Oury is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Superoxide dismutase & Pulmonary fibrosis. The author has an hindex of 59, co-authored 156 publications receiving 10621 citations. Previous affiliations of Tim D. Oury include Durham University & Duke University.
Papers
More filters
Journal ArticleDOI
Extracellular superoxide dismutase in biology and medicine.
TL;DR: This review will discuss the regulation of EC-SOD and its role in a variety of oxidant-mediated diseases.
Journal ArticleDOI
Copper,zinc superoxide dismutase is primarily a cytosolic protein in human cells
TL;DR: The intracellular localization of human copper,zinc superoxide dismutase (Cu,Zn-SOD; superoxide:superoxide oxidoreductase, EC 1.15.1.1) was evaluated by using EM immunocytochemistry and both isolated human cell lines and human tissues to identify the soluble cytosolic protein.
Journal ArticleDOI
Oxidative stress in pulmonary fibrosis: a possible role for redox modulatory therapy.
TL;DR: Investigation into therapeutic approaches to inhibit oxidant-mediated reactions in the initiation and progression of pulmonary fibrosis may provide hope for the future treatment of this disease.
Journal ArticleDOI
Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis.
Xiaomei Wang,Yingze Zhang,Hong Pyo Kim,Zhihong Zhou,Carol Feghali-Bostwick,Fang Liu,Emeka Ifedigbo,Xiaohui Xu,Tim D. Oury,Naftali Kaminski,Augustine M.K. Choi +10 more
TL;DR: Cav-1 was able to suppress TGF-β1–induced ECM production in cultured fibroblasts through the regulation of the c-Jun N-terminal kinase (JNK) pathway and suggests a novel therapeutic target for patients with pulmonary fibrosis.
Journal ArticleDOI
Animal models of fibrotic lung disease.
Bethany B. Moore,William Lawson,William Lawson,Tim D. Oury,Thomas H. Sisson,Krishnan Raghavendran,Cory M. Hogaboam +6 more
TL;DR: Each of the models reviewed in this report offers a powerful tool for studying some aspect of fibrotic lung disease and has a much better understanding of the fact that the aged lung has increased susceptibility to fibrosis.