F
Fang Liu
Researcher at University of Pittsburgh
Publications - 28
Citations - 2944
Fang Liu is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 15, co-authored 18 publications receiving 2783 citations. Previous affiliations of Fang Liu include The University of Nottingham Ningbo China & Tsinghua University.
Papers
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Journal ArticleDOI
Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury
Leo E. Otterbein,Brian S. Zuckerbraun,Manabu Haga,Fang Liu,Ruiping Song,Anny Usheva,Christina Stachulak,Natalya Bodyak,R. Neal Smith,Eva Csizmadia,Shivraj Tyagi,Yorihiro Akamatsu,Richard J Flavell,Timothy R. Billiar,Edith Tzeng,Fritz H. Bach,Augustine M.K. Choi,Miguel P. Soares,Miguel P. Soares +18 more
TL;DR: Findings demonstrate a protective role for CO in vascular injury and support its use as a therapeutic agent.
Journal ArticleDOI
Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis.
Xiaomei Wang,Yingze Zhang,Hong Pyo Kim,Zhihong Zhou,Carol Feghali-Bostwick,Fang Liu,Emeka Ifedigbo,Xiaohui Xu,Tim D. Oury,Naftali Kaminski,Augustine M.K. Choi +10 more
TL;DR: Cav-1 was able to suppress TGF-β1–induced ECM production in cultured fibroblasts through the regulation of the c-Jun N-terminal kinase (JNK) pathway and suggests a novel therapeutic target for patients with pulmonary fibrosis.
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Protection Against Ischemia/Reperfusion Injury in Cardiac and Renal Transplantation with Carbon Monoxide, Biliverdin and Both
Atsunori Nakao,Joao Seda Neto,Shinichi Kanno,Donna B. Stolz,Kei Kimizuka,Fang Liu,Fritz H. Bach,Timothy R. Billiar,Augustine M.K. Choi,Leo E. Otterbein,Noriko Murase +10 more
TL;DR: The study shows that the addition of byproducts of heme degradation with different mechanisms of action provides enhanced protection against transplant‐associated cold I/R injury of heart and kidney grafts.
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Mitochondrial localization and function of heme oxygenase-1 in cigarette smoke-induced cell death.
Dirk-Jan Slebos,Stefan W. Ryter,Marco van der Toorn,Fang Liu,Fengli Guo,Catherine J. Baty,Jenny M. Karlsson,Simon C. Watkins,Hong Pyo Kim,Xue Wang,Janet S. Lee,Dirkje S. Postma,Henk F. Kauffman,Augustine M.K. Choi +13 more
TL;DR: The functional compartmentalization of heme oxygenase-1 in the mitochondria of lung epithelial cells, and its potential role in defense against mitochondria-mediated cell death during CSE exposure are demonstrated.
Journal ArticleDOI
Carbon Monoxide Protects against Liver Failure through Nitric Oxide–induced Heme Oxygenase 1
Brian S. Zuckerbraun,Timothy R. Billiar,Sherrie L. Otterbein,Peter K.M. Kim,Fang Liu,Augustine M.K. Choi,Fritz H. Bach,Leo E. Otterbein +7 more
TL;DR: When protection from cell death is initiated by CO, NO production and HO-1 activity are each required for the protective effect showing for the first time an essential synergy between these two molecules in tandem providing potent cytoprotection.