H
Hong Pyo Kim
Researcher at University of Ulsan
Publications - 54
Citations - 8747
Hong Pyo Kim is an academic researcher from University of Ulsan. The author has contributed to research in topics: Programmed cell death & Heme oxygenase. The author has an hindex of 34, co-authored 53 publications receiving 7897 citations. Previous affiliations of Hong Pyo Kim include UPRRP College of Natural Sciences & Brigham and Women's Hospital.
Papers
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Journal ArticleDOI
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
Kiichi Nakahira,Jeffrey A. Haspel,Jeffrey A. Haspel,Vijay A. K. Rathinam,Seon Jin Lee,Tamas Dolinay,Hilaire C. Lam,Joshua A. Englert,Marlene Rabinovitch,Manuela Cernadas,Hong Pyo Kim,Hong Pyo Kim,Katherine A. Fitzgerald,Stefan W. Ryter,Augustine M.K. Choi +14 more
TL;DR: This study suggests that autophagic proteins regulate NALP3-dependent inflammation by preserving mitochondria integrity and cytosolic translocation of mitochondrial DNA in response to lipopolysaccharide and ATP in macrophages.
Journal ArticleDOI
Mechanisms of cell death in oxidative stress.
Stefan W. Ryter,Hong Pyo Kim,Alexander Hoetzel,Jeong W. Park,Kiichi Nakahira,Xue Wang,Augustine M.K. Choi +6 more
TL;DR: Cell death mechanisms have been studied across a broad spectrum of models of oxidative stress, including H2O2, nitric oxide and derivatives, endotoxin-induced inflammation, photodynamic therapy, ultraviolet-A and ionizing radiations, and cigarette smoke.
Journal ArticleDOI
Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease
Zhi Hua Chen,Hong Pyo Kim,Hong Pyo Kim,Frank C. Sciurba,Seon Jin Lee,Seon Jin Lee,Carol Feghali-Bostwick,Donna B. Stolz,Rajiv Dhir,Rodney J. Landreneau,Mathew J. Schuchert,Samuel A. Yousem,Kiichi Nakahira,Kiichi Nakahira,Joseph M. Pilewski,Janet S. Lee,Yingze Zhang,Stefan W. Ryter,Stefan W. Ryter,Augustine M.K. Choi +19 more
TL;DR: A critical role for Egr-1 is demonstrated in promoting autophagy and apoptosis in response to cigarette smoke exposure in vitro and in vivo, suggesting novel therapeutic targets for the treatment of cigarette smoke induced lung injury.
Journal ArticleDOI
Co as a cellular signaling molecule
TL;DR: Recent findings reveal that HO-derived CO may act as an oxygen sensor and circadian modulator of heme biosynthesis and, in lymphocytes, CO may participate in regulatory T cell function.
Journal ArticleDOI
Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis.
Xiaomei Wang,Yingze Zhang,Hong Pyo Kim,Zhihong Zhou,Carol Feghali-Bostwick,Fang Liu,Emeka Ifedigbo,Xiaohui Xu,Tim D. Oury,Naftali Kaminski,Augustine M.K. Choi +10 more
TL;DR: Cav-1 was able to suppress TGF-β1–induced ECM production in cultured fibroblasts through the regulation of the c-Jun N-terminal kinase (JNK) pathway and suggests a novel therapeutic target for patients with pulmonary fibrosis.