T
Tim Stearns
Researcher at Stanford University
Publications - 189
Citations - 15312
Tim Stearns is an academic researcher from Stanford University. The author has contributed to research in topics: Centrosome & Centriole. The author has an hindex of 60, co-authored 181 publications receiving 13957 citations. Previous affiliations of Tim Stearns include University of Illinois at Urbana–Champaign & Genentech.
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Journal ArticleDOI
γ-Tubulin is a highly conserved component of the centrosome
TL;DR: The cloned and characterized gamma-tubulin genes from both X. laevis and S. pombe are very similar to each other and to the original Aspergillus protein, indicating that Gamma-tubulins are an ubiquitous and highly conserved subfamily of the tubulin family.
Journal ArticleDOI
The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries
Erich A. Nigg,Tim Stearns +1 more
TL;DR: The spatial aspects of the centrosome duplication cycle, the mechanism of centriole assembly and the possible consequences of the inherent asymmetry of Centrosomes and centrosomes are discussed.
Book ChapterDOI
Fluorescence microscopy methods for yeast.
John R. Pringle,Robert A. Preston,Alison E.M. Adams,Tim Stearns,David G. Drubin,Brian Haarer,Elizabeth W. Jones +6 more
TL;DR: This chapter reviews and provides detailed protocols for the application of immunofluorescence and other fluorescence-microscopic procedures to yeast and shows that these methods are effective with other yeasts such as Schizosaccharomyces pombe and Candida albicans.
Journal ArticleDOI
Microtubules Orient the Mitotic Spindle in Yeast through Dynein-dependent Interactions with the Cell Cortex
Janet L. Carminati,Tim Stearns +1 more
TL;DR: Results indicate that microtubules and dynein interact to produce dynamic cortical interactions, and that these interactions result in the force driving spindle orientation.
Journal ArticleDOI
Mechanism limiting centrosome duplication to once per cell cycle
Meng-Fu Bryan Tsou,Tim Stearns +1 more
TL;DR: It is proposed that the ‘once-only’ control of centrosome duplication is achieved by temporally separating licensing in anaphase from growth of new centrioles during S phase, which suggests that re-duplication ofcentrioles within a cell cycle is prevented by centriole engagement itself.