T
Todd K. Rosengart
Researcher at Baylor College of Medicine
Publications - 250
Citations - 10633
Todd K. Rosengart is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Medicine & Coronary artery disease. The author has an hindex of 53, co-authored 228 publications receiving 9709 citations. Previous affiliations of Todd K. Rosengart include Michael E. DeBakey Veterans Affairs Medical Center in Houston & NewYork–Presbyterian Hospital.
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Journal ArticleDOI
Angiogenesis Gene Therapy Phase I Assessment of Direct Intramyocardial Administration of an Adenovirus Vector Expressing VEGF121 cDNA to Individuals With Clinically Significant Severe Coronary Artery Disease
Todd K. Rosengart,Leonard Y. Lee,Shailen R. Patel,Timothy A. Sanborn,Manish Parikh,Geoffrey Bergman,Rory Hachamovitch,Massimiliano Szulc,Paul Kligfield,Peter M. Okin,Rebecca T. Hahn,Richard B. Devereux,Martin R. Post,Neil R. Hackett,Taliba Foster,Tina M. Grasso,Martin Lesser,O. Wayne Isom,Ronald G. Crystal +18 more
TL;DR: The data are consistent with the concept that direct myocardial administration of Ad(GV)VEGF121.10 to individuals with clinically significant coronary artery disease appears to be well tolerated, and initiation of phase II evaluation of this therapy is warranted.
Journal ArticleDOI
Clinical Trials in Coronary Angiogenesis: Issues, Problems, Consensus An Expert Panel Summary
Michael Simons,Robert O. Bonow,N. A. Chronos,David J. Cohen,F. J. Giordano,H. K. Hammond,Roger J. Laham,W. Li,M. Pike,Frank W. Sellke,T. J. Stegmann,James E. Udelson,Todd K. Rosengart +12 more
TL;DR: A panel of experts actively working in the field is convened during the 72nd meeting of the American Heart Association to define and achieve a consensus on the challenges facing development of therapeutic angiogenesis for coronary disease.
Journal ArticleDOI
Outcomes of 3309 thoracoabdominal aortic aneurysm repairs.
Joseph S. Coselli,Joseph S. Coselli,Joseph S. Coselli,Scott A. LeMaire,Ourania Preventza,Ourania Preventza,Ourania Preventza,Kim I. de la Cruz,Kim I. de la Cruz,Kim I. de la Cruz,Denton A. Cooley,Matt D. Price,Matt D. Price,Alan P. Stolz,Alan P. Stolz,Susan Y. Green,Susan Y. Green,Courtney N. Arredondo,Todd K. Rosengart +18 more
TL;DR: The data suggest that thoracoabdominal aortic aneurysm repair, when performed at an experienced center, can produce respectable outcomes and predictors of early death and other adverse postoperative outcomes are described.
Journal ArticleDOI
Vascular Endothelial Growth Factor Is the Major Angiogenic Factor in Omentum: Mechanism of the Omentum-Mediated Angiogenesis
Qing-Xue Zhang,Christopher J. Magovern,Charles A. Mack,Kurt T. Budenbender,Wilson Ko,Todd K. Rosengart +5 more
TL;DR: Data suggest that VEGF is the major angiogenic factor produced by omentum and possibly underlies the mechanism of omentsum-induced angiogenesis.
Journal ArticleDOI
Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart
Charles A. Mack,Shailen R. Patel,Eric A. Schwarz,Pat B. Zanzonico,Rebecca T. Hahn,Arzu Ilercil,Richard B. Devereux,Stanley J. Goldsmith,Timothy F. Christian,Timothy A. Sanborn,Imre Kovesdi,Neil R. Hackett,O. Wayne Isom,Ronald G. Crystal,Todd K. Rosengart +14 more
TL;DR: An Ad vector expressing the VEGF121 cDNA induces collateral vessel development in ischemic myocardium and results in significant improvement in both myocardial perfusion and function.